Lu Yun, Wang Bao-Lei
Department of Hepatobiliary Surgery, Affiliated Hospital of Medical College, Qingdao University, Qingdao, China.
Am J Med Sci. 2009 Mar;337(3):195-8. doi: 10.1097/MAJ.0b013e318182ee45.
The sea cucumbers growing in the estuary of the Pohai of northern China are called Stichopus japonicus and are the orthodox holothurians in traditional Chinese medicine. There are multiple biological active ingredients in S. japonicus, and S. japonicus acid mucopolysaccharide (SJAMP) is one of the important ingredients. SJAMP has multiple pharmacologic actions, such as antitumor, immunologic regulation, anticoagulated blood, and antivirus. The research on antitumor has been carried out by way of animal experiments aiming at studying internal tumor-inhibiting effect of SJAMP, and the route of administration is usually peritoneal or intragastric. Additionally, sea cucumbers have been widely recognized and applied as medicated food or therapeutic prescriptions during and after the treatment of some tumors.
生长在中国北方渤海湾河口的海参被称为刺参，是传统中药中的正宗海参。刺参含有多种生物活性成分，其中刺参酸性粘多糖（SJAMP）是重要成分之一。SJAMP具有多种药理作用，如抗肿瘤、免疫调节、抗凝血和抗病毒等。针对SJAMP体内抑瘤作用，已通过动物实验开展了抗肿瘤研究，给药途径通常为腹腔注射或灌胃。此外，海参在一些肿瘤治疗期间及之后作为药膳或治疗方剂已得到广泛认可和应用。
