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猫的巨核细胞性骨髓增生症

Megakaryocytic myelosis in a cat.

作者信息

Michel R L, O'Handley P, Dade A W

出版信息

J Am Vet Med Assoc. 1976 Jun 1;168(11):1021-5.

PMID:931768
Abstract

A myeloproliferative disorder in a cat was characterized by abnormal proliferation of megakaryocytes in the bone marrow and by severe, nonregenerative anemia. The number of circulating thrombocytes was increased markedly, with many giant and morphologically bizarre forms. Terminally, the circulating blood contained large numbers of undifferentiated blast cells. The spleen and liver were infiltrated by megakaryocytes and mononuclear mesenchymal cells of uncertain identity.

摘要

一只猫的骨髓增殖性疾病的特征是骨髓中巨核细胞异常增殖以及严重的非再生性贫血。循环血小板数量显著增加,有许多巨大且形态怪异的形态。终末期,循环血液中含有大量未分化的原始细胞。脾脏和肝脏被身份不明的巨核细胞和单核间充质细胞浸润。

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