Kliniken Schmieder Konstanz, Konstanz, Germany.
Acta Neurol Scand. 2009 Oct;120(4):251-7. doi: 10.1111/j.1600-0404.2008.01152.x. Epub 2009 Jan 28.
Effects of endurance training in multiple sclerosis (MS) patients complaining of motor fatigue.
Thirty MS patients complaining of fatigue with low to moderate disabilities randomly allocated to the intervention (thrice weekly 45-min intervals of endurance exercise) or control treatment (three 45-min episodes of stretching, balance training and coordination), both as 'add-on' therapy for 3 weeks during inpatient rehabilitation.
Maximal walking distance before intervention averaged 1043 +/- 568 and 1163 +/- 750 m in the two groups. The intervention group increased its maximal walking distance by 650 +/- 474 m. The control group extended its walking distance by 96 +/- 70 m.
The present data confirm a strong effect of endurance exercise on maximal walking distance. Remarkably, there were no parallel improvements on the Modified Fatigue Impact Scale, the Beck Depression Inventory and the Hamburg Quality of Life Questionnaire for MS.
探讨耐力训练对多发性硬化症（MS）患者运动性疲劳的影响。
30 名主诉疲劳且残疾程度为低中度的 MS 患者被随机分配至干预组（每周 3 次、每次 45 分钟的耐力运动）或对照组（每周 3 次、每次 45 分钟的伸展、平衡和协调训练），均作为住院康复期间的附加治疗，持续 3 周。
干预前，两组的最大步行距离平均为 1043±568m 和 1163±750m。干预组的最大步行距离增加了 650±474m，对照组增加了 96±70m。
本研究数据证实了耐力运动对最大步行距离有显著影响。值得注意的是，在改良疲劳影响量表、贝克抑郁量表和汉堡多发性硬化生活质量问卷上均未观察到平行改善。
