[Research on the effect of phenylethanoid glycosides (PEG) of the Cistanche deserticola on anti-aging in aged mice induced by D-galactose].

OBJECTIVE

To investigate the effect of Phenylethanoid glycosides (PEG) of the Cistanche deserticola on anti-aging in aged mice induced by D-galactose.

METHODS

Taking Vitamin E as the positive control, after administration of high and low dose of the PEG, detected the learning and memory ability, the activities of SOD, the content of MDA and organ index.

RESULTS

Compared with the model group, the abilities of learning and memorizing were improved in PEG groups. The activity of SOD was enhanced significantly in serum and brain. The MDA content of liver and serum was decreased. The PEG also improved the Index of spleen and thymus.

CONCLUSION

The PEG of Cistanche deserticola can enhance the ability of learning, memorizing, anti-oxidation, and improve immune function.