Ishimaru Yoshiro
Department of Applied Biological Chemistry, Graduate School of Agricultural and Life Sciences, The University of Tokyo, Tokyo, Japan.
Odontology. 2009 Jan;97(1):1-7. doi: 10.1007/s10266-008-0095-y. Epub 2009 Jan 29.
Among the five senses, taste and olfaction play crucial roles in the detection of chemical substances in the environment and are referred to as chemical senses. In the past decade, much progress has been made in studies on molecular mechanisms of the gustatory system by methods such as those based on molecular and cellular biology, genetics, and bioinformatics. This review covers recent studies on taste receptors, intracellular signaling transduction in taste receptor cells, and taste coding at the periphery in vertebrates from fish to mammals.
在五种感官中，味觉和嗅觉在检测环境中的化学物质方面起着关键作用，被称为化学感官。在过去十年中，通过基于分子和细胞生物学、遗传学以及生物信息学等方法，味觉系统的分子机制研究取得了很大进展。这篇综述涵盖了从鱼类到哺乳动物等脊椎动物味觉受体、味觉受体细胞内信号转导以及外周味觉编码的最新研究。
