Sino-Britain Joint Laboratory, College of Pharmaceutical Sciences, Zhejiang University, Hangzhou, Zhejiang 310058, China.
Evid Based Complement Alternat Med. 2011;2011:713274. doi: 10.1093/ecam/nep001. Epub 2010 Oct 19.
The objective of this study is to explore the effects of acupuncture and auricular acupressure in relieving menopausal hot flashes of bilaterally ovariectomized Chinese women. Between May 2006 and March 2008, 46 bilaterally ovariectomized Chinese women were randomized into an acupuncture and auricular acupressure group (n = 21) and a hormone replacement therapy (HRT) group (Tibolone, n = 25). Each patient was given a standard daily log and was required to record the frequency and severity of hot flashes and side effects of the treatment felt daily, from 1 week before the treatment started to the fourth week after the treatment ended. The serum levels of follicle stimulating hormone (FSH), LH and E(2) were detected before and after the treatment. After the treatment and the follow-up, both the severity and frequency of hot flashes in the two groups were relieved significantly when compared with pre-treatment (P < .05). There was no significant difference in the severity of hot flashes between them after treatment (P > .05), while after the follow-up, the severity of hot flashes in the HRT group was alleviated more. After the treatment and the follow-up, the frequency of menopausal hot flashes in the HRT group was reduced more (P < .05). After treatment, the levels of FSH decreased significantly and the levels of E(2) increased significantly in both groups (P < .05), and they changed more in the HRT group (P < .05). Acupuncture and auricular acupressure can be used as alternative treatments to relieve menopausal hot flashes for those bilaterally ovariectomized women who are unable or unwilling to receive HRT.
本研究旨在探讨针灸和耳压对缓解双侧卵巢切除术后中国女性更年期潮热的影响。2006 年 5 月至 2008 年 3 月,46 例双侧卵巢切除术后中国女性患者随机分为针灸和耳压组(n = 21)和激素替代治疗组(替勃龙,n = 25)。每位患者均接受标准的日常记录,并要求记录治疗开始前 1 周至治疗结束后第 4 周每日潮热的频率和严重程度,以及治疗的副作用。治疗前后检测血清卵泡刺激素(FSH)、黄体生成素(LH)和 E2 水平。治疗和随访后,两组潮热的严重程度和频率均较治疗前明显缓解(P < 0.05)。治疗后两组潮热严重程度无明显差异(P > 0.05),但随访后 HRT 组潮热严重程度缓解更明显。治疗和随访后,HRT 组潮热频率降低更明显(P < 0.05)。治疗后两组 FSH 水平显著降低,E2 水平显著升高(P < 0.05),HRT 组变化更明显(P < 0.05)。针灸和耳压可作为双侧卵巢切除术后无法或不愿接受 HRT 的女性缓解更年期潮热的替代治疗方法。