Refaat Rania, Harth Marc, Proschek Petra, Lindemayr Sebastian, Vogl Thomas J
Department of Diagnostic and Interventional Radiology, Johann-Wolfgang-Goethe University, Frankfurt am Main, Germany.
Pediatr Radiol. 2009 Apr;39(4):389-92. doi: 10.1007/s00247-008-1132-2. Epub 2009 Feb 4.
We report a case of histopathologically proven autoimmune pancreatitis in an 11-year-old boy. Abdominal US and MRI showed a focal swelling of the pancreatic head, the latter also showing delayed contrast enhancement. There was diffuse irregular pancreatic duct narrowing, compression of the intrapancreatic common bile duct, and mild proximal biliary dilatation on MR cholangiopancreatography. Laboratory results revealed normal serum IgG and subclass 4 with negative autoimmune antibodies, and slightly elevated carbohydrate antigen 19-9. This highlights the differentiation of autoimmune pancreatitis from pancreatic head cancer and, to a lesser extent, other forms of pancreatitis in children.
我们报告一例经组织病理学证实的11岁男孩自身免疫性胰腺炎病例。腹部超声和磁共振成像显示胰头局灶性肿胀,磁共振成像还显示延迟强化。磁共振胰胆管造影显示胰管弥漫性不规则狭窄、胰内胆总管受压及近端胆管轻度扩张。实验室检查结果显示血清免疫球蛋白G及4亚类正常,自身免疫抗体阴性,糖类抗原19-9轻度升高。这突出了自身免疫性胰腺炎与胰头癌的鉴别,在较小程度上也突出了与儿童其他形式胰腺炎的鉴别。