Markin A A, Morukov B V, Zhuravleva O A, Zabolotskaia I V, Vostrikova L V, Liapunova N A, Tsvetkova T G
Aviakosm Ekolog Med. 2008 Sep-Oct;42(5):56-9.
Blood samples were taken from 8 volunteers (21 to 26 years of age) for 7-day immersion 7 days prior to, on days 3 and 7 of the experiment and on days 1 and 8 of recovery. Serum was analyzed for 38 biochemical markers of the functional state of the myocardium, skeletal muscles, hepatobiliary system, kidney, pancreas, GI tract, prostate, and protein-nucleic, carbohydrate, electrolyte and mineral metabolism. Seven-day immersion was found to alter the biochemical parameters within the physiological norm boundaries. The observed changes included lower activities of enzymes associated with muscular and myocardial constellation, shifts in electrolytes (K, Na, Mg), and increases in the biliary function parameters. Increased concentrations of the lipid metabolism parameters suggest a higher risk of atherogenesis. Biochemical parameters of bone tissues and erythrocyte activity were essentially unchanged. Most of the parameters returned to pre-experimental values by day 8 of recovery.
在实验前7天、实验第3天和第7天以及恢复第1天和第8天,采集了8名志愿者(21至26岁)的血样,进行为期7天的浸泡实验。对血清进行了分析,检测了心肌、骨骼肌、肝胆系统、肾脏、胰腺、胃肠道、前列腺以及蛋白质 - 核酸、碳水化合物、电解质和矿物质代谢的38种生化标志物。结果发现,为期7天的浸泡在生理正常范围内改变了生化参数。观察到的变化包括与肌肉和心肌相关的酶活性降低、电解质(钾、钠、镁)的变化以及胆汁功能参数的增加。脂质代谢参数浓度升高表明动脉粥样硬化风险更高。骨组织和红细胞活性的生化参数基本未变。大多数参数在恢复第8天恢复到实验前的值。