Leigh Y, Goldacre M, McCulloch P
Nuffield Department of Surgery, University of Oxford, John Radcliffe Hospital, Headley Way, Headington, Oxford, UK.
Eur J Surg Oncol. 2009 Aug;35(8):820-5. doi: 10.1016/j.ejso.2008.11.004. Epub 2009 Feb 5.
Mortality after oesophagectomy is lower in high-volume than in low-volume surgical units. Case series from cardiothoracic surgeons report lower mortality rates than those from general surgeons. We therefore used a national data set to investigate the effects of surgical specialty and volume on mortality after oesophagectomy.
We analysed Hospital Episode Statistics for oesophagectomy for cancer (n=9034 cases), linked to data from death certificates, in England from 1998 to 2003.
After adjustment for patients' age, sex and deprivation score, the odds ratio (OR) for death of general surgeons' (GS) patients, compared with cardiothoracic surgeons' (CTS) patients, was significantly high: 1.62 [95% CI 1.34-1.96] at 30 days and 1.38 [1.18-1.61] at 90 days. The odds ratio for high-volume GS patients was not significantly different from that for high-volume CTS patients. However, the odds ratio for low-volume GS patients compared with high-volume CTS patients was significantly high: 1.72 (1.40-2.11) at 30 days and 1.48 (1.26-1.74) at 90 days.
Patients treated by general surgeons in low-volume hospitals had worse mortality outcomes than those treated by general surgeons in high-volume hospitals or by cardiothoracic surgeons. This is important because a majority of patients who underwent oesophagectomy for cancer were in this high-mortality risk group.
在高手术量的外科单位,食管癌切除术后的死亡率低于低手术量的单位。心胸外科医生的病例系列报告的死亡率低于普通外科医生。因此,我们使用全国数据集来研究手术专科和手术量对食管癌切除术后死亡率的影响。
我们分析了1998年至2003年英格兰癌症食管癌切除术的医院事件统计数据(n = 9034例),并与死亡证明数据相关联。
在对患者的年龄、性别和贫困评分进行调整后,普通外科医生(GS)患者的死亡比值比(OR)与心胸外科医生(CTS)患者相比显著更高:30天时为1.62 [95%可信区间1.34 - 1.96],90天时为1.38 [1.18 - 1.61]。高手术量GS患者的比值比与高手术量CTS患者无显著差异。然而,低手术量GS患者与高手术量CTS患者相比的比值比显著更高:30天时为1.72(1.40 - 2.11),90天时为1.48(1.26 - 1.74)。
在低手术量医院接受普通外科医生治疗的患者,其死亡率结果比在高手术量医院接受普通外科医生治疗或接受心胸外科医生治疗的患者更差。这很重要,因为大多数接受癌症食管癌切除术的患者属于这一高死亡风险组。