Tan Lili, Cai Zhi-Qiang, Lai Nai-Shin
Singapore Polytechnic Optometry Centre, School of Chemical and Life Sciences, Singapore.
Cont Lens Anterior Eye. 2009 Apr;32(2):78-83. doi: 10.1016/j.clae.2008.09.003. Epub 2009 Feb 6.
To investigate the accuracy and sensitivity of the Thermo-Tracer TH9100MV, NEC San-ei in monitoring the temperature of the anterior eye surface and to establish an inter-subjects ocular surface temperature (OST) norm in Chinese young adults.
A blackbody with fixed temperature was used to study accuracy and sensitivity of the thermal camera used (Thermo-Tracer TH9100MV, NEC San-ei). Sixty healthy Chinese young adults aged 17-21 (mean age 19) were recruited from the Singapore Polytechnic Optometry Centre. A room with standard room temperature and humidity was used. Subjects were adapted to the room conditions for 20min before measurement. OST was then measured within 4-5s after a blink and with their upper lid lifted by a cotton bud, using infrared thermo-camera, in a non-invasive manner.
All future Thermo-Tracer readings could be converted to 'true' temperature via the regression equation derived y=1.0884x - 3.4026 (r(2)=0.9985), where y is the 'true' temperature and x is reading by Thermo-Tracer. Sensitivity of the machine for all 16 temperatures studied was found to be 91.3%. Mean OST for the population studied was 34.70+/-0.50 degrees C. Mean OST at geometrical centre cornea (GCC) was 34.39+/-0.47 degrees C and inter-ocular temperature difference was approximately 0.20+/-0.15 degrees C. Both the horizontal and vertical OST profile was established. No significant differences between right/left eyes and between genders were found at 95% CI.
Findings on the accuracy can be used as a reference by researchers who are using the same infrared thermal camera. It is proven that the machine has high sensitivity in determining the temperature of anterior ocular surface. Methodology used in this study can also be applied to the determination of the accuracy and sensitivity of the dynamic range for other infrared thermal cameras. Inter-subjects OST norm in Chinese young adults aged 17-21 was established.
研究NEC San-ei的Thermo-Tracer TH9100MV在监测眼前表面温度方面的准确性和敏感性，并建立中国年轻成年人的受试者间眼表温度（OST）标准。
使用固定温度的黑体来研究所用热成像仪（NEC San-ei的Thermo-Tracer TH9100MV）的准确性和敏感性。从新加坡理工学院验光中心招募了60名年龄在17 - 21岁（平均年龄19岁）的健康中国年轻成年人。使用一个具有标准室温和湿度的房间。在测量前，受试者在该房间条件下适应20分钟。然后在眨眼后4 - 5秒内，用棉签抬起上睑，使用红外热成像仪以非侵入性方式测量OST。
所有未来的Thermo-Tracer读数都可以通过推导的回归方程y = 1.0884x - 3.4026（r² = 0.9985）转换为“真实”温度，其中y是“真实”温度，x是Thermo-Tracer的读数。发现该机器对所研究的所有16个温度的敏感性为91.3%。所研究人群的平均OST为34.70±0.50℃。角膜几何中心（GCC）的平均OST为34.39±0.47℃，眼间温差约为0.20±0.15℃。建立了水平和垂直的OST分布图。在95%置信区间内，左右眼之间以及性别之间均未发现显著差异。
关于准确性的研究结果可供使用相同红外热成像仪的研究人员参考。已证明该机器在确定眼前表面温度方面具有高敏感性。本研究中使用的方法也可应用于确定其他红外热成像仪动态范围的准确性和敏感性。建立了17 - 21岁中国年轻成年人的受试者间OST标准。
