Mayou R, Blackwood R, Bryant B, Garnham J
University Department of Psychiatry, Warneford Hospital, Oxford, U.K.
J Psychosom Res. 1991;35(4-5):399-407. doi: 10.1016/0022-3999(91)90035-m.
The associations between exercise capacity, symptoms and specific aspects of quality of life were examined in subjects participating in a trial of the treatment of heart failure. Patients were assessed on entry and after three months treatment. The principle symptoms were fatigue, breathlessness and chest pain. These limited the extent and speed of physical activities, restricted social, leisure and family life and were associated with emotional distress. There were associations between baseline exercise capacity and measures of quality of life. Change in exercise capacity during three months treatment was correlated with changes in measures of symptoms, limitation of activity and quality of life. The findings confirm the value of change in exercise capacity as a measure of functional status and suggest that it should be supported by a limited number of specific measures of quality of life.
在参与心力衰竭治疗试验的受试者中，研究了运动能力、症状与生活质量特定方面之间的关联。患者在入组时和治疗三个月后接受评估。主要症状为疲劳、呼吸急促和胸痛。这些症状限制了体力活动的程度和速度，限制了社交、休闲和家庭生活，并与情绪困扰相关。基线运动能力与生活质量指标之间存在关联。治疗三个月期间运动能力的变化与症状、活动受限和生活质量指标的变化相关。这些发现证实了运动能力变化作为功能状态衡量指标的价值，并表明它应由有限数量的特定生活质量指标来支持。
