College of Medicine, National Taiwan University, Taipei, Taiwan, Republic of China.
J Physiother. 2011;57(3):157-63. doi: 10.1016/S1836-9553(11)70036-4.
Are anxiety and depression correlated with physical function, disability, and quality of life in people with chronic heart failure? Does 8 weeks of home-based exercise improve anxiety, depression, physical function, disability, and quality of life in these patients? Do the changes in these outcomes correlate?
Randomised trial.
51 people with clinically stable chronic heart failure were randomised into an experimental group (n=24) or a control group (n=27).
The experimental group undertook an individualised home-based exercise program, 30 minutes per session, 3 sessions per week for 8 weeks, with regular telephone follow-up and consultations. The control group maintained their usual activity during this period.
The Hospital Anxiety and Depression Scale, six-minute walk test, Groningen Activity Restriction Scale, and Minnesota Living with Heart Failure Questionnaire were administered at baseline and 8 weeks.
At baseline, anxiety and depression were inversely moderately correlated with walking distance, activity, and quality of life. Compared with controls, the experimental group improved significantly more in their walking distance (by 21m, 95% CI 7 to 36) and their quality of life (by 7 points on the 105-point Minnesota score, 95% CI 1 to 12). In the experimental group, the changes in quality of life correlated moderately strongly with changes in anxiety (r=0.539, p=0.01).
Anxiety and depression were associated with physical function, disability, and quality of life in people with chronic heart failure. Home-based exercise improved quality of life and physical function significantly but not psychological status in these patients.
焦虑和抑郁与慢性心力衰竭患者的身体功能、残疾和生活质量相关吗？8 周的家庭为基础的运动是否能改善这些患者的焦虑、抑郁、身体功能、残疾和生活质量？这些结果的变化是否相关？
随机试验。
51 名临床稳定的慢性心力衰竭患者被随机分为实验组（n=24）和对照组（n=27）。
实验组进行个体化家庭运动计划，每次 30 分钟，每周 3 次，持续 8 周，定期电话随访和咨询。对照组在这段时间内保持他们的日常活动。
在基线和 8 周时使用医院焦虑和抑郁量表、六分钟步行测试、格罗宁根活动限制量表和明尼苏达州心力衰竭生活质量问卷进行测量。
在基线时，焦虑和抑郁与步行距离、活动和生活质量呈中度负相关。与对照组相比，实验组在步行距离（增加 21m，95%置信区间 7 至 36）和生活质量（明尼苏达州评分增加 7 分，95%置信区间 1 至 12）方面有显著改善。在实验组中，生活质量的变化与焦虑的变化中度相关（r=0.539，p=0.01）。
焦虑和抑郁与慢性心力衰竭患者的身体功能、残疾和生活质量相关。家庭为基础的运动显著改善了这些患者的生活质量和身体功能，但对心理状态没有影响。
