Hashida Shin-nosuke, Takahashi Hideyuki, Uchimiya Hirofumi
Institute of Molecular and Cellular Biosciences, The University of Tokyo, 1-1-1 Yayoi, Bunkyo-ku, Tokyo 113-0032, Japan.
Ann Bot. 2009 Apr;103(6):819-24. doi: 10.1093/aob/mcp019. Epub 2009 Feb 5.
Pyridine nucleotides are essential for electron transport and serve as co-factors in multiple metabolic processes in all organisms. Each nucleotide has a particular role in metabolism. For instance, the NAD/NADP ratio is believed to be responsible for sustaining the functional status of plant cells. However, since enzymes involved in the synthesis and degradation of NAD and NADP have not been fully identified, the physiological functions of these co-enzymes in plant growth and development are largely unknown.
This Botanical Briefing covers progress in the developmental and stress-related roles of genes associated with NAD biosynthesis in plants. Special attention will be given to assessments of physiological impacts through the modulation of NAD and NADP biosynthesis.
The significance of NAD biosynthesis in plant development and NADP biosynthesis in plant stress tolerance is summarized in this Briefing. Further investigation of cells expressing a set of NAD biosynthetic genes would facilitate understanding of regulatory mechanisms by which plant cells maintain NAD homeostasis.
吡啶核苷酸对于电子传递至关重要，并在所有生物体的多个代谢过程中作为辅助因子。每种核苷酸在代谢中都有特定作用。例如，NAD/NADP 比率被认为负责维持植物细胞的功能状态。然而，由于参与 NAD 和 NADP 合成与降解的酶尚未完全确定，这些辅酶在植物生长发育中的生理功能在很大程度上仍不清楚。
本植物学简报涵盖了与植物中 NAD 生物合成相关基因在发育和胁迫相关作用方面的进展。将特别关注通过调节 NAD 和 NADP 生物合成对生理影响的评估。
本简报总结了 NAD 生物合成在植物发育中的意义以及 NADP 生物合成在植物胁迫耐受性中的意义。进一步研究表达一组 NAD 生物合成基因的细胞将有助于理解植物细胞维持 NAD 稳态的调控机制。
