植物中聚（ADP - 核糖）聚合酶的沉默改变非生物胁迫信号转导。
Silencing of poly(ADP-ribose) polymerase in plants alters abiotic stress signal transduction.
作者信息
Vanderauwera Sandy, De Block Marc, Van de Steene Nancy, van de Cotte Brigitte, Metzlaff Michael, Van Breusegem Frank
机构信息
Department of Plant Systems Biology, Flanders Institute for Biotechnology (VIB), Technologiepark 927, 9052 Ghent, Belgium.
出版信息
Proc Natl Acad Sci U S A. 2007 Sep 18;104(38):15150-5. doi: 10.1073/pnas.0706668104. Epub 2007 Sep 6.
Abstract
Transgenic plants with reduced poly(ADP-ribose) polymerase (PARP) levels have broad-spectrum stress-resistant phenotypes. Both Arabidopsis thaliana and oilseed rape (Brassica napus) lines overexpressing RNA interference-PARP constructs were more resistant to various abiotic stress treatments in laboratory and greenhouse experiments without negative effects on growth, development, and seed production. This outperforming stress tolerance was initially attributed solely to a maintained energy homeostasis due to reduced NAD(+) consumption. We show that in PARP2-deficient Arabidopsis plants, the observed abiotic stress resistance can also be explained by alterations in abscisic acid levels that facilitate the induction of a wide set of defense-related genes.
摘要
聚（ADP - 核糖）聚合酶（PARP）水平降低的转基因植物具有广谱抗逆表型。在实验室和温室实验中，过表达RNA干扰PARP构建体的拟南芥和油菜（甘蓝型油菜）品系对各种非生物胁迫处理更具抗性，且对生长、发育和种子生产没有负面影响。这种卓越的胁迫耐受性最初仅归因于由于NAD(+)消耗减少而维持的能量稳态。我们表明，在PARP2缺陷的拟南芥植物中，观察到的非生物胁迫抗性也可以通过脱落酸水平的改变来解释，这种改变促进了一系列与防御相关基因的诱导。
相似文献
1
Silencing of poly(ADP-ribose) polymerase in plants alters abiotic stress signal transduction.植物中聚（ADP - 核糖）聚合酶的沉默改变非生物胁迫信号转导。
Proc Natl Acad Sci U S A. 2007 Sep 18;104(38):15150-5. doi: 10.1073/pnas.0706668104. Epub 2007 Sep 6.
2
New perspectives on the plant PARP family: Arabidopsis PARP3 is inactive, and PARP1 exhibits predominant poly (ADP-ribose) polymerase activity in response to DNA damage.植物 PARP 家族的新视角：拟南芥 PARP3 无活性，而 PARP1 在响应 DNA 损伤时表现出主要的多聚（ADP-核糖）聚合酶活性。
BMC Plant Biol. 2019 Aug 19;19(1):364. doi: 10.1186/s12870-019-1958-9.
3
Analysis of knockout mutants reveals non-redundant functions of poly(ADP-ribose)polymerase isoforms in Arabidopsis.对基因敲除突变体的分析揭示了拟南芥中聚（ADP - 核糖）聚合酶亚型的非冗余功能。
Plant Mol Biol. 2015 Nov;89(4-5):319-38. doi: 10.1007/s11103-015-0363-5. Epub 2015 Oct 1.
4
Poly(ADP-ribose) polymerase in plants affects energy homeostasis, cell death and stress tolerance.植物中的聚（ADP-核糖）聚合酶影响能量稳态、细胞死亡和胁迫耐受性。
Plant J. 2005 Jan;41(1):95-106. doi: 10.1111/j.1365-313X.2004.02277.x.
5
Synthesis and degradation of poly(ADP-ribose) in plants.植物中多聚（ADP-核糖）的合成与降解。
Front Biosci (Landmark Ed). 2014 Jun 1;19(8):1436-44. doi: 10.2741/4294.
6
PARP2 Is the Predominant Poly(ADP-Ribose) Polymerase in Arabidopsis DNA Damage and Immune Responses.PARP2是拟南芥DNA损伤和免疫反应中的主要聚（ADP - 核糖）聚合酶。
PLoS Genet. 2015 May 7;11(5):e1005200. doi: 10.1371/journal.pgen.1005200. eCollection 2015 May.
7
A yeast growth assay to characterize plant poly(ADP-ribose) polymerase (PARP) proteins and inhibitors.一种用于表征植物聚（ADP - 核糖）聚合酶（PARP）蛋白和抑制剂的酵母生长测定法。
Anal Biochem. 2017 Jun 15;527:20-23. doi: 10.1016/j.ab.2017.04.002. Epub 2017 Apr 10.
8
Analysis of poly(ADP-Ribose) polymerases in Arabidopsis telomere biology.拟南芥端粒生物学中聚（ADP - 核糖）聚合酶的分析
PLoS One. 2014 Feb 13;9(2):e88872. doi: 10.1371/journal.pone.0088872. eCollection 2014.
9
Poly(ADP-Ribose) Polymerases in Plants and Their Human Counterparts: Parallels and Peculiarities.植物中的多聚（ADP-核糖）聚合酶及其人类对应物：相似与独特之处。
Int J Mol Sci. 2019 Apr 2;20(7):1638. doi: 10.3390/ijms20071638.
10
Arabidopsis sirtuins and poly(ADP-ribose) polymerases regulate gene expression in the day but do not affect circadian rhythms.拟南芥的 Sirtuins 和多聚（ADP-核糖）聚合酶在白天调节基因表达，但不影响昼夜节律。
Plant Cell Environ. 2021 May;44(5):1451-1467. doi: 10.1111/pce.13996. Epub 2021 Feb 18.
引用本文的文献
1
Exogenous dopamine application ameliorates chilling injury and preserves quality of kiwifruit during cold storage.外源多巴胺处理可减轻猕猴桃在冷藏期间的冷害并保持其品质。
Sci Rep. 2025 Jan 23;15(1):2894. doi: 10.1038/s41598-025-87542-2.
2
Specific and shared biological functions of PARP2 - is PARP2 really a lil' brother of PARP1?PARP2的特异性和共享生物学功能——PARP2真的是PARP1的“小弟”吗？
Expert Rev Mol Med. 2024 May 3;26:e13. doi: 10.1017/erm.2024.14.
3
The Ser/Thr protein kinase FonKin4-poly(ADP-ribose) polymerase FonPARP1 phosphorylation cascade is required for the pathogenicity of watermelon fusarium wilt fungus f. sp. .丝氨酸/苏氨酸蛋白激酶FonKin4-聚（ADP-核糖）聚合酶FonPARP1磷酸化级联反应是西瓜枯萎病菌致病所必需的。
Front Microbiol. 2024 Apr 16;15:1397688. doi: 10.3389/fmicb.2024.1397688. eCollection 2024.
4
Unveiling synergistic QTLs associated with slow wilting in soybean (Glycine max [L.] Merr.).揭示与大豆（Glycine max [L.] Merr.）缓慢萎蔫相关的协同 QTL。
Theor Appl Genet. 2024 Mar 19;137(4):85. doi: 10.1007/s00122-024-04585-1.
5
Phosphoribosyltransferases and Their Roles in Plant Development and Abiotic Stress Response.磷酸核糖基转移酶及其在植物发育和非生物胁迫响应中的作用。
Int J Mol Sci. 2023 Jul 23;24(14):11828. doi: 10.3390/ijms241411828.
6
Salt-tolerant endophytic bacterium B30 enhance bermudagrass growth under salt stress by modulating plant physiology and changing rhizosphere and root bacterial community.耐盐内生细菌B30通过调节植物生理以及改变根际和根系细菌群落来促进盐胁迫下狗牙根的生长。
Front Plant Sci. 2022 Aug 2;13:959427. doi: 10.3389/fpls.2022.959427. eCollection 2022.
7
Genome-wide association study of Senegalese sorghum seedlings responding to a Texas isolate of Colletotrichum sublineola.全基因组关联研究塞内加尔高粱幼苗对科氏炭疽菌德克萨斯分离物的反应。
Sci Rep. 2022 Jul 29;12(1):13025. doi: 10.1038/s41598-022-16844-6.
8
Role of Poly(ADP-Ribose) Polymerase (PARP) Enzyme in the Systemic Acquired Acclimation Induced by Light Stress in L. Plants.聚（ADP - 核糖）聚合酶（PARP）在光胁迫诱导的L.植物系统获得性驯化中的作用。
Plants (Basel). 2022 Jul 18;11(14):1870. doi: 10.3390/plants11141870.
9
Redox status of the plant cell determines epigenetic modifications under abiotic stress conditions and during developmental processes.植物细胞的氧化还原状态决定了非生物胁迫条件下和发育过程中的表观遗传修饰。
J Adv Res. 2022 Dec;42:99-116. doi: 10.1016/j.jare.2022.04.007. Epub 2022 Apr 28.
10
Overexpression of nicotinamidase 3 (NIC3) gene and the exogenous application of nicotinic acid (NA) enhance drought tolerance and increase biomass in Arabidopsis.尼克酰胺酶 3（NIC3）基因的过表达和烟碱酸（NA）的外源应用增强了拟南芥的耐旱性并增加了生物量。
Plant Mol Biol. 2021 Sep;107(1-2):63-84. doi: 10.1007/s11103-021-01179-z. Epub 2021 Aug 30.
本文引用的文献
1
NAD - new roles in signalling and gene regulation in plants.NAD——植物信号传导和基因调控中的新作用。
New Phytol. 2004 Jul;163(1):31-44. doi: 10.1111/j.1469-8137.2004.01087.x.
2
Anthocyanins in vegetative tissues: a proposed unified function in photoprotection.营养组织中的花青素：光保护作用的一种统一假说
New Phytol. 2002 Sep;155(3):349-361. doi: 10.1046/j.1469-8137.2002.00482.x.
3
The AtGenExpress global stress expression data set: protocols, evaluation and model data analysis of UV-B light, drought and cold stress responses.拟南芥基因表达谱全球胁迫表达数据集：UV-B光、干旱和冷胁迫响应的实验方案、评估及模型数据分析
Plant J. 2007 Apr;50(2):347-63. doi: 10.1111/j.1365-313X.2007.03052.x. Epub 2007 Mar 21.
4
Nicotinamidase participates in the salvage pathway of NAD biosynthesis in Arabidopsis.烟酰胺酶参与拟南芥中烟酰胺腺嘌呤二核苷酸生物合成的补救途径。
Plant J. 2007 Mar;49(6):1020-9. doi: 10.1111/j.1365-313X.2006.03013.x.
5
Overexpressing a NAM, ATAF, and CUC (NAC) transcription factor enhances drought resistance and salt tolerance in rice.过表达一个NAM、ATAF和CUC（NAC）转录因子可增强水稻的抗旱性和耐盐性。
Proc Natl Acad Sci U S A. 2006 Aug 29;103(35):12987-92. doi: 10.1073/pnas.0604882103. Epub 2006 Aug 21.
6
Poly(ADP-ribose): novel functions for an old molecule.聚（ADP - 核糖）：一种古老分子的新功能。
Nat Rev Mol Cell Biol. 2006 Jul;7(7):517-28. doi: 10.1038/nrm1963.
7
Reactive oxygen species in plant cell death.植物细胞死亡中的活性氧
Plant Physiol. 2006 Jun;141(2):384-90. doi: 10.1104/pp.106.078295.
8
NAD(P) synthesis and pyridine nucleotide cycling in plants and their potential importance in stress conditions.植物中的NAD(P)合成与吡啶核苷酸循环及其在胁迫条件下的潜在重要性。
J Exp Bot. 2006;57(8):1603-20. doi: 10.1093/jxb/erj202. Epub 2006 May 19.
9
Understanding regulatory networks and engineering for enhanced drought tolerance in plants.理解调控网络并进行工程设计以增强植物的耐旱性。
Curr Opin Plant Biol. 2006 Apr;9(2):189-95. doi: 10.1016/j.pbi.2006.01.019. Epub 2006 Feb 17.
10
Unraveling abiotic stress tolerance mechanisms--getting genomics going.解析非生物胁迫耐受机制——推动基因组学发展。
Curr Opin Plant Biol. 2006 Apr;9(2):180-8. doi: 10.1016/j.pbi.2006.01.003. Epub 2006 Feb 2.
Zotero 插件