Alvarez-Moya E M, Jiménez-Murcia S, Moragas L, Gómez-Peña M, Aymamí M N, Ochoa C, Sánchez-Díaz I, Menchón J M, Fernández-Aranda F
Department of Psychiatry, Bellvitge University Hospital, Barcelona, Spain.
J Int Neuropsychol Soc. 2009 Mar;15(2):302-6. doi: 10.1017/S1355617709090377. Epub 2009 Feb 10.
Shared vulnerabilities have been described across disorders of impulse control, including pathological gambling (PG) and bulimia nervosa (BN). Our aim was to compare the executive functioning of PG and BN females in order to confirm their similarity at a neurocognitive level. A total of 15 BN females, 15 PG females, and 15 healthy control (HC) females were administered the Wisconsin Card Sorting Test (WCST) and the Stroop Color and Word Test. Analysis of covariance adjusted for age and education was conducted to compare groups. PG showed the greatest impairment, that is, the highest percentage of WCST perseverative errors (p = .023), the lowest percentage of conceptual-level responses (p = .034), and the highest number of total trials administered (p = .021), while BN showed the highest percentage of WCST nonperseverative errors (p = .003). Both BN and PG females demonstrated executive dysfunction relative to HCs but different specific correlates (i.e., greater vulnerability to distraction in BN, but more cognitive inflexibility in PG).
冲动控制障碍，包括病理性赌博（PG）和神经性贪食症（BN），已被描述存在共同的易感性。我们的目的是比较PG和BN女性的执行功能，以确认她们在神经认知水平上的相似性。对15名BN女性、15名PG女性和15名健康对照（HC）女性进行了威斯康星卡片分类测验（WCST）和斯特鲁普颜色和文字测验。进行了年龄和教育程度校正的协方差分析以比较各组。PG表现出最大的损害，即WCST持续性错误的百分比最高（p = 0.023），概念水平反应的百分比最低（p = 0.034），以及施测的总试验次数最多（p = 0.021），而BN表现出WCST非持续性错误的百分比最高（p = 0.003）。相对于HCs，BN和PG女性均表现出执行功能障碍，但存在不同的特定相关性（即，BN更容易受到干扰，而PG则表现出更多的认知灵活性）。
