Zhu Xiang-Wei, Liu Shu-Shen, Ge Hui-Lin, Liu Yan
Key Laboratory of Eco-environments in Three Gorges Reservoir Region, Ministry of Education, College of Life Science, Southwest University, Chongqing 400715, PR China.
Water Res. 2009 Apr;43(6):1731-9. doi: 10.1016/j.watres.2009.01.004. Epub 2009 Jan 22.
The bioluminescence inhibition of six triazine herbicides including desmetryne (DES), simetryn (SIM), velpar (VEL), prometon (PRO), metribuzin (MET), and aminotriazine (AMI) on Vibrio qinghaiensis sp.-Q67 (Q67) was determined to investigate the effects of exposure duration on the ecotoxicological relevance of triazine herbicides. Based on the short-term microplate toxicity analysis (MTA), a long-term MTA was established to assess the impact of exposure time on the toxicities of the herbicides. The results show that the long-term toxicities of DES and SIM are similar to their short-term toxicities, and the long-term toxicities of VEL, PRO, and MET are higher than their short-term toxicities, while AMI without short-term toxicity has a high long-term toxicity. In addition, a parabolic relationship was found between the pEC(50) (the negative logarithm of the EC(50), log 1/EC(50)) and the logarithm of octanol-water partition coefficient (logK(ow)). To better understand their toxicity process, the time-dependent toxicities of the six herbicides on Q67 were determined over a period of 12 h during which measurements were taken every 30 min to generate an integral effect surface related to both concentration and duration.
测定了包括去草净（DES）、西草净（SIM）、百草枯（VEL）、扑灭通（PRO）、嗪草酮（MET）和氨三嗪（AMI）在内的六种三嗪类除草剂对青海弧菌Q67（Q67）的生物发光抑制作用，以研究暴露持续时间对三嗪类除草剂生态毒理学相关性的影响。基于短期微孔板毒性分析（MTA），建立了长期MTA来评估暴露时间对除草剂毒性的影响。结果表明，DES和SIM的长期毒性与其短期毒性相似，VEL、PRO和MET的长期毒性高于其短期毒性，而无短期毒性的AMI具有较高的长期毒性。此外，发现pEC(50)（EC(50)的负对数，log 1/EC(50)）与正辛醇-水分配系数的对数（logK(ow)）之间存在抛物线关系。为了更好地了解它们的毒性过程，在12小时内测定了六种除草剂对Q67的时间依赖性毒性，在此期间每30分钟进行一次测量，以生成与浓度和持续时间相关的综合效应表面。
