Hahn Fletcher F, Roszell Laurie E, Daxon Eric G, Guilmette Raymond A, Parkhurst Mary Ann
Lovelace Respiratory Research Institute, 2425 Ridgecrest Drive SE, Albuquerque, NM 87105, USA.
Health Phys. 2009 Mar;96(3):352-62. doi: 10.1097/01.hp.0000318891.68749.66.
Assessment of the health risk from exposure to aerosols of depleted uranium (DU) is an important outcome of the Capstone aerosol studies that established exposure ranges to personnel in armored combat vehicles perforated by DU munitions. Although the radiation exposure from DU is low, there is concern that DU deposited in the body may increase cancer rates. Radiation doses to various organs of the body resulting from the inhalation of DU aerosols measured in the Capstone studies were calculated using International Commission on Radiological Protection (ICRP) models. Organs and tissues with the highest calculated committed equivalent 50-y doses were lung and extrathoracic tissues (nose and nasal passages, pharynx, larynx, mouth, and thoracic lymph nodes). Doses to the bone surface and kidney were about 5 to 10% of the doses to the extrathoracic tissues. Organ-specific risks were estimated using ICRP and U.S. Environmental Protection Agency (EPA) methodologies. Risks for crewmembers and first responders were determined for selected scenarios based on the time interval of exposure and for vehicle and armor type. The lung was the organ with the highest cancer mortality risk, accounting for about 97% of the risks summed from all organs. The highest mean lifetime risk for lung cancer for the scenario with the longest exposure time interval (2 h) was 0.42%. This risk is low compared with the natural or background risk of 7.35%. These risks can be significantly reduced by using an existing ventilation system (if operable) and by reducing personnel time in the vehicle immediately after perforation.
评估接触贫铀(DU)气溶胶的健康风险是顶点气溶胶研究的一项重要成果,该研究确定了被DU弹药击穿的装甲战车中人员的接触范围。尽管DU产生的辐射暴露很低,但人们担心沉积在体内的DU可能会增加患癌率。顶点研究中测量的吸入DU气溶胶对身体各器官产生的辐射剂量是使用国际放射防护委员会(ICRP)模型计算得出的。计算得出的50年 committed等效剂量最高的器官和组织是肺和胸外组织(鼻子和鼻道、咽、喉、口腔和胸部淋巴结)。骨表面和肾脏的剂量约为胸外组织剂量的5%至10%。使用ICRP和美国环境保护局(EPA)的方法估算了特定器官的风险。根据暴露的时间间隔以及车辆和装甲类型,针对选定场景确定了机组人员和第一响应者的风险。肺是癌症死亡风险最高的器官,约占所有器官汇总风险的97%。暴露时间间隔最长(2小时)的场景中,肺癌的最高平均终生风险为0.42%。与7.35%的自然或背景风险相比,该风险较低。通过使用现有的通风系统(如果可操作)以及在穿孔后立即减少人员在车内的时间,这些风险可以显著降低。