Li Winnie Z M, Li Jun, Bi Cathy W C, Cheung Anna W H, Huang Wen, Duan Ran, Choi Roy C Y, Chen Ivy S Y, Zhao Kui J, Dong Tina T X, Duan Jin A, Tsim Karl W K
Department of Biology and Center for Chinese Medicine, The Hong Kong University of Science and Technology, Hong Kong, PR China.
Planta Med. 2009 May;75(6):602-6. doi: 10.1055/s-0029-1185361. Epub 2009 Feb 9.
Herein, we test the hypothesis that a member of a formulated Chinese herbal decoction cannot be replaced by another herb. Danggui Buxue Tang (DBT) is being used as an example for illustration: this is a traditional decoction containing Radix Astragali (RA) and Radix Angelicae Sinensis (RAS) in a weight ratio of 5 to 1. Rhizoma Chuanxiong (RC) and RAS are two chemically very similar herbs but with a distinct function. Following the preparation method of DBT, a herbal decoction, namely Chuanxiong Buxue Tang (CBT), was created, which contained RA and RC in a weight ratio of 5 to 1. The two decoctions, DBT and CBT, were compared in parallel regarding their chemical and biological properties. In all the tested parameters, DBT showed superior properties, both chemically and biologically, to that of CBT. The current results reveal the uniqueness of Chinese herbal decoctions that require a well-defined formulation, which is indispensable for its specific composition.
在此，我们检验了一个假设，即配方中的一味中药不能被另一味中药所替代。以当归补血汤（DBT）为例进行说明：这是一种传统汤剂，由黄芪（RA）和当归（RAS）按重量比5:1组成。川芎（RC）和RAS是两种化学性质非常相似但功能不同的中药。按照DBT的制备方法，制备了一种含RA和RC重量比为5:1的中药汤剂，即川芎补血汤（CBT）。对DBT和CBT这两种汤剂的化学和生物学特性进行了平行比较。在所有测试参数中，DBT在化学和生物学方面均表现出优于CBT的特性。目前的结果揭示了中药汤剂的独特性，即需要明确的配方，这对于其特定的组成是不可或缺的。
