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空气污染物与呼吸系统:毒性及药物干预措施

Air pollutants and the respiratory system: toxicity and pharmacologic interventions.

作者信息

Koenig J Q, Pierson W E

机构信息

Department of Environmental Health, University of Washington, Seattle 98195.

出版信息

J Toxicol Clin Toxicol. 1991;29(3):401-11. doi: 10.3109/15563659109000366.

DOI:10.3109/15563659109000366
PMID:1920573
Abstract

Air pollution remains a major aggravation of respiratory symptoms and disease. Sulfur dioxide, ozone, sulfuric acid, particulate matter such as the fine particles from wood smoke, and nitrogen dioxide all produce significant effects when investigated in laboratory or field studies. These effects are decreases in pulmonary function and evidence of inflammation as well as suggestions of increases in chronic respiratory disease. Asthmatic subjects may be the group at greatest risk from air pollutants. Common medications used to treat asthma have varying effects on blocking or mitigating these pollutant-induced effects.

摘要

空气污染仍然是呼吸道症状和疾病的主要加重因素。在实验室或实地研究中,二氧化硫、臭氧、硫酸、诸如木烟中的细颗粒物等颗粒物以及二氧化氮都会产生显著影响。这些影响包括肺功能下降、炎症迹象以及慢性呼吸道疾病增加的迹象。哮喘患者可能是受空气污染物影响风险最大的群体。用于治疗哮喘的常用药物在阻断或减轻这些污染物诱发的影响方面有不同的效果。

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引用本文的文献

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Environ Health Perspect. 1995 Sep;103 Suppl 6(Suppl 6):209-11. doi: 10.1289/ehp.95103s6209.