Beutelspacher S C, Schmidbauer J M
Augenklinik, Klinikum Nürnberg, Prof. Ernst-Nathan-Strasse 1, Nürnberg.
Klin Monbl Augenheilkd. 2009 Feb;226(2):115-9. doi: 10.1055/s-2008-1027913. Epub 2009 Feb 10.
The aim of this study was to compare macular thickness measurements obtained from time-domain optical coherence tomography (OCT) and spectral-domain OCT to evaluate their agreement.
Fifty randomly assigned subjects were included. Twenty-five were male, twenty-five female. In all cases both eyes were measured. Serial measurements were obtained from time-domain (StratusOCT, Zeiss) and spectral-domain OCT (Heidelberg Engineering, Germany). Total and regional macular thicknesses were obtained from both machines. Their agreement was estimated by Bland Altman plots.
The foveal and total macular thicknesses measured by 3D OCT were significantly greater than those measured by StratusOCT (p < 0.001).
While both time-domain and spectral-domain OCTs are reliable for macular thickness measurements, spectral-domain OCT delivers significantly higher values for macular thickness compared to the time-domain OCT. Macular measurements obtained from the two OCT systems may not be used interchangeably.
本研究旨在比较时域光学相干断层扫描（OCT）和频域OCT所测得的黄斑厚度，以评估它们之间的一致性。
纳入50名随机分组的受试者。其中25名男性，25名女性。所有受试者均测量双眼。分别用时域（StratusOCT，蔡司公司）和频域OCT（德国海德堡工程公司）进行连续测量。两台仪器均获取黄斑区整体及局部厚度数据。通过Bland Altman图评估两者的一致性。
3D OCT测量的黄斑中心凹及黄斑区整体厚度显著大于StratusOCT测量值（p < 0.001）。
虽然时域和频域OCT在测量黄斑厚度方面均可靠，但与时域OCT相比，频域OCT测得的黄斑厚度值显著更高。不能互换使用这两种OCT系统所获得的黄斑测量数据。
