Anderson Robin E, Chan Warren C W
Institute of Biomaterials & Biomedical Engineering, Centre for Biomaterials and Biomolecular Research, University of Toronto, Toronto, ON, Canada.
ACS Nano. 2008 Jul;2(7):1341-52. doi: 10.1021/nn700450g.
The successful transfer of nanoparticles between solvents is critical for many applications. We evaluated the impact of amphiphilic polymer composition on the size, transfer efficiency, and biocompatibility of tri-n-octylphosphine oxide/hexadecylamine-stabilized semiconductor ZnS-capped CdSe and CdS-capped CdTe(x)Se(1-x) quantum dots (QDs). We also investigated the adsorption of various proteins onto the surface of these QDs and studied the effect of surface chemistry on non-specific protein binding. The results from these studies will have implications in the design of QDs and other nanoparticles for biological and biomedical applications.
纳米颗粒在不同溶剂之间的成功转移对许多应用而言至关重要。我们评估了两亲聚合物组成对三正辛基氧化膦/十六烷基胺稳定的半导体硫化锌包覆的硒化镉量子点以及硫化镉包覆的碲化镉硒量子点（量子点）的尺寸、转移效率和生物相容性的影响。我们还研究了各种蛋白质在这些量子点表面的吸附情况，并探讨了表面化学对非特异性蛋白质结合的影响。这些研究结果将对用于生物和生物医学应用的量子点及其他纳米颗粒的设计产生影响。
