Wellinghausen Nele, Moericke Angelika, Bundschuh Silke, Friedrich Wilhelm, Schulz Ansgar S, Gatz Susanne A
Institute of Medical Microbiology and Hygiene, University Hospital of Ulm, Ulm, Germany.
University Hospital for Children's and Adolescent Medicine, Ulm, Germany.
J Med Microbiol. 2009 Mar;58(Pt 3):386-390. doi: 10.1099/jmm.0.003970-0.
Candida dubliniensis is an emerging fungal pathogen, especially in immunodeficient patients. We report what is to the best of our knowledge the first case of multifocal osteomyelitis following disseminated infection in a patient after haematopoietic stem cell transplantation. PFGE for typing of C. dubliniensis was developed and the necessity of long-term antifungal therapy is discussed.
都柏林念珠菌是一种新出现的真菌病原体,尤其在免疫缺陷患者中。据我们所知,我们报告了首例造血干细胞移植患者播散性感染后发生多灶性骨髓炎的病例。我们开发了用于都柏林念珠菌分型的脉冲场凝胶电泳(PFGE),并讨论了长期抗真菌治疗的必要性。