Moragues M D, Omaetxebarria M J, Elguezabal N, Bikandi J, Quindós G, Coleman D C, Pontón J
Departamento de Enfermería I, Facultad de Medicina y Odontología, Universidad del País Vasco, E-48080 Bilbao, Vizcaya, Spain.
J Clin Microbiol. 2001 Aug;39(8):2999-3001. doi: 10.1128/JCM.39.8.2999-3001.2001.
Using a rabbit model of systemic infection, we show that it is possible to differentiate infections caused by Candida dubliniensis and other Candida species by detecting the antibody response mounted by the infected animals. These results confirm our previous observation in a patient with C. dubliniensis candidemia and suggest that detection of C. dubliniensis-specific antibodies is useful in the diagnosis of invasive candidiasis caused by this yeast.
利用兔全身性感染模型,我们发现通过检测受感染动物产生的抗体反应,能够区分由都柏林念珠菌和其他念珠菌属引起的感染。这些结果证实了我们之前对一名患有都柏林念珠菌血症患者的观察,并表明检测都柏林念珠菌特异性抗体有助于诊断由该酵母菌引起的侵袭性念珠菌病。