Prasad Kashi Nath, Prasad Amit, Verma Avantika, Singh Aloukick Kumar
Department of Microbiology, Sanjay Gandhi Postgraduate Institute of Medical Sciences, Lucknow 226 014, India.
J Biosci. 2008 Nov;33(4):571-82. doi: 10.1007/s12038-008-0075-y.
Cysticercosis, caused by Taenia solium larva is a major public health problem,especially in the developing world and neurocysticercosis (NCC) is considered to be the most common parasitic infestation of the central nervous system. NCC is identified as the single most common cause of community acquired active epilepsy; 26.3% to 53.8% active epilepsy cases in the developing world including India and Latin America are due to NCC.It is also becoming more common in the developed world because of increased migration of people with the disease or Taenia solium carriers and frequent travel to the endemic countries. It is estimated that three quarters of the estimated 50 million people with active epilepsy live in the poor countries of the world. Recent Indian studies using neuroimaging techniques suggest that the disease burden in India surpasses many other developing countries. Hence it is important to know the epidemiology,pathogenesis and diagnostic criteria so as to assess the disease burden and adopt interventional strategies for its control.Literature search was done for this review with special emphasis on Indian studies to create awareness about the disease in India,since cysticercosis is preventable and potentially eradicable.
由猪带绦虫幼虫引起的囊尾蚴病是一个主要的公共卫生问题,尤其是在发展中世界,而神经囊尾蚴病(NCC)被认为是中枢神经系统最常见的寄生虫感染。NCC被确定为社区获得性活动性癫痫的单一最常见病因;在包括印度和拉丁美洲在内的发展中世界,26.3%至53.8%的活动性癫痫病例归因于NCC。由于患病者或猪带绦虫携带者的迁移增加以及频繁前往流行国家,该病在发达国家也越来越常见。据估计,全世界约5000万活动性癫痫患者中有四分之三生活在贫穷国家。印度最近使用神经影像学技术的研究表明,印度的疾病负担超过了许多其他发展中国家。因此,了解其流行病学、发病机制和诊断标准对于评估疾病负担并采取干预策略进行控制很重要。为撰写本综述进行了文献检索,特别侧重于印度的研究,以提高印度对该病的认识,因为囊尾蚴病是可预防的且有可能根除。