Graduate School of Pharmaceutical Sciences, Hokkaido University, Sapporo 060-0812, Japan.
J Nat Prod. 2009 Mar 27;72(3):488-91. doi: 10.1021/np800645q.
Four new bromopyrrole alkaloids, nagelamides O (1) and P (2) and mukanadins E (3) and F (4), were isolated from three collections of Okinawan marine sponges of the genus Agelas. The structures and stereochemistry of 1-4 were elucidated on the basis of their spectroscopic data.
从三种冲绳海洋海绵属 Agelas 中分离得到四个新的溴代吡咯生物碱:nagelamides O(1)和 P(2)以及 mukuanadins E(3)和 F(4)。根据它们的光谱数据阐明了 1-4 的结构和立体化学。