来自太平洋海绵的具有独特苯并环丁烷骨架的苯并西普菌素A和B以及纳格拉酰胺S和T。
Benzosceptrins A and B with a unique benzocyclobutane skeleton and nagelamide S and T from Pacific sponges.
作者信息
Appenzeller Jérôme, Tilvi Supriya, Martin Marie-Thérèse, Gallard Jean-François, El-bitar Hoda, Dau Elise Tran Huu, Debitus Cécile, Laurent Dominique, Moriou Céline, Al-Mourabit Ali
机构信息
Centre de Recherche de Gif-sur-Yvette, Institut de Chimie des Substances Naturelles, UPR 2301, CNRS, Avenue de la Terrasse, 91198 Gif-sur-Yvette, France.
出版信息
Org Lett. 2009 Nov 5;11(21):4874-7. doi: 10.1021/ol901946h.
Four new dimeric pyrrole-2-aminoimidazole alkaloids have been isolated from the Pacific marine sponges Agelas cf. mauritiana and Phakellia sp. They include the unusual C2 symmetrical benzosceptrins A (4) and B (5), which each possess a unique benzocyclobutane skeleton and nagelamides S (6) and T (7). Their structures and relative configuration were elucidated from spectroscopic data. Plausible biogenetic paths for these compounds are also proposed in this paper.
从太平洋海洋海绵Agelas cf. mauritiana和Phakellia sp.中分离出了四种新的二聚体吡咯-2-氨基咪唑生物碱。它们包括不寻常的C2对称苯并截短侧耳素A（4）和B（5），它们各自具有独特的苯并环丁烷骨架以及纳盖酰胺S（6）和T（7）。通过光谱数据阐明了它们的结构和相对构型。本文还提出了这些化合物可能的生物合成途径。
Zotero 插件