Ma Lei, Li Ruoyu, Yu Jin, Wang Chen, Wan Zhe, Wang Xiaohong
Department of Dermatology/Research Center for Medical Mycology, Peking University First Hospital, Beijing, PR China.
Med Mycol. 2009 May;47(3):312-6. doi: 10.1080/13693780802562951. Epub 2008 Feb 11.
The authors report a case of Majocchi's granuloma and onychomycosis in a liver transplant recipient caused by a Trichophyton spp., phenotypically consistent with Trichophyton rubrum var. raubitschekii. A 48-year-old female patient who had undergone liver transplantation nine months earlier, presented with red papules and nodular lesions on her back, buttock and thigh of two months duration. She also had onychomycosis of toe nails for a few years, which worsened post transplant. Two fungal isolates were derived from her infected toe nails and nodular tissue. Physical, pathological and mycological examination, including KOH preparation, fungal culture and DNA sequencing of the internal transcribed spacer(ITS) of rRNA were performed. The clinical diagnosis was Majocchi's granuloma and onychomycosis caused by the Trichophyton rubrum var. raubitschekii. This is the first case report of this organism from China.
作者报告了一例肝移植受者发生的Majocchi肉芽肿和甲癣，由一株毛癣菌属引起，其表型与红色毛癣菌鲁比切克变种一致。一名48岁女性患者，9个月前接受了肝移植，背部、臀部和大腿出现红色丘疹和结节性病变，持续两个月。她的脚趾甲患有甲癣数年，移植后病情加重。从她感染的脚趾甲和结节组织中分离出两种真菌。进行了体格、病理和真菌学检查，包括氢氧化钾制片、真菌培养以及rRNA内转录间隔区（ITS）的DNA测序。临床诊断为鲁比切克变种红色毛癣菌引起的Majocchi肉芽肿和甲癣。这是来自中国的该菌种的首例病例报告。
