Langner M D, Maibach H I
Department of Dermatology, University of California at San Francisco, San Francisco, CA, USA.
Skin Therapy Lett. 2009 Jan;14(1):3-5.
Photosensitivity is defined as responsiveness to light exposure. For many common dermatologic drugs, proper storage conditions are essential for maintaining drug activity. Degradation and loss of activity can occur with exposure to light, temperature, and/ or moisture. For example, ketoconazole degrades after 24 hours of light exposure. In this article storage guidelines for common dermatology drugs are provided. We suspect that drug degradation is common due to improper storage and that improved patient instruction regarding storage will reduce degradation and alleviate some of the danger associated with improper storage and usage patterns.
光敏性被定义为对光照的反应性。对于许多常见的皮肤科药物而言，适当的储存条件对于维持药物活性至关重要。暴露于光、温度和/或湿度下会导致药物降解和活性丧失。例如，酮康唑在光照24小时后会降解。本文提供了常见皮肤科药物的储存指南。我们怀疑由于储存不当，药物降解很常见，并且改善关于储存的患者指导将减少降解并减轻一些与不当储存和使用模式相关的危险。
