子宫内膜异位症不孕患者手术治疗前后的胚胎质量
Embryo quality before and after surgical treatment of endometriosis in infertile patients.
作者信息
Shahine Lora K, Burney Richard O, Behr Barry, Milki Amin A, Westphal Lynn M, Lathi Ruth B
机构信息
Division of Reproductive Endocrinology and Infertility, Department of Obstetrics and Gynecology, Stanford University, 900 Welch Road, Suite 350, Stanford, CA 94304, USA.
出版信息
J Assist Reprod Genet. 2009 Mar;26(2-3):69-73. doi: 10.1007/s10815-008-9287-1. Epub 2009 Feb 12.
PURPOSE
To investigate the hypothesis that surgical treatment of endometriosis in infertile patients may improve pregnancy rates by improving embryo quality.
METHODS
We conducted a retrospective evaluation of 30 infertile patients treated with in vitro fertilization (IVF) before and after surgery for endometriosis. Patients served as their own controls and only cycles with similar stimulation protocols were compared.
RESULTS
Using standard visual evaluation, embryo quality on day 3 was similar before and after surgical treatment of endometriosis. Fifty seven percent of patients had stage I-II endometriosis and 43% had stage III-IV disease. No patients had a live birth after the first IVF cycle and 43% of patients had a live birth with the IVF cycle after surgery.
CONCLUSIONS
Surgical treatment of endometriosis does not alter embryo quality in patients with infertility treated with IVF.
目的
探讨子宫内膜异位症不孕患者的手术治疗是否可通过改善胚胎质量提高妊娠率这一假说。
方法
我们对30例子宫内膜异位症不孕患者在手术前后接受体外受精（IVF）治疗的情况进行了回顾性评估。患者自身作为对照，仅比较采用相似刺激方案的周期。
结果
采用标准视觉评估，子宫内膜异位症手术治疗前后第3天的胚胎质量相似。57%的患者患有I-II期子宫内膜异位症，43%患有III-IV期疾病。首次IVF周期后无患者活产，43%的患者术后IVF周期活产。
结论
子宫内膜异位症的手术治疗不会改变接受IVF治疗的不孕患者的胚胎质量。
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