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哌甲酯对注意力缺陷多动障碍儿童在单任务和双任务条件下姿势稳定性的影响——一项双盲随机对照试验。

The effect of methylphenidate on postural stability under single and dual task conditions in children with attention deficit hyperactivity disorder - a double blind randomized control trial.

作者信息

Jacobi-Polishook Talia, Shorer Zamir, Melzer Itshak

机构信息

Schwartz Movement Analysis & Rehabilitation Laboratory, Department of Physical Therapy, Faculty of Health Sciences, Ben-Gurion University of the Negev, Beer-Sheva, Israel.

出版信息

J Neurol Sci. 2009 May 15;280(1-2):15-21. doi: 10.1016/j.jns.2009.01.007. Epub 2009 Feb 13.

DOI:10.1016/j.jns.2009.01.007
PMID:19217632
Abstract

OBJECTIVES

To investigate the effects of Methylphenidate (MPH) on postural stability in attention deficit hyperactivity disorder (ADHD) children in single and dual task conditions.

METHODS

A randomized controlled double-blind study analyzing postural stability in 24 ADHD children before and after MPH vs. placebo treatments, in three task conditions: (1) Single task, standing still; (2) dual task, standing still performing a memory-attention demanding task; (3) standing still listening to music.

RESULTS

MPH resulted in a significant improvement in postural stability during the dual task condition and while listening to music, with no equivalent improvement in placebo controls.

CONCLUSIONS

MPH improves postural stability in ADHD, especially when an additional task is performed. This is probably due to enhanced attention abilities, thus contributing to improved balance control during performance of tasks that require attention. MPH remains to be studied as a potential drug treatment to improve balance control and physical functioning in other clinical populations.

摘要

目的

研究哌甲酯(MPH)在单任务和双任务条件下对注意力缺陷多动障碍(ADHD)儿童姿势稳定性的影响。

方法

一项随机对照双盲研究,分析24名ADHD儿童在接受MPH与安慰剂治疗前后,在三种任务条件下的姿势稳定性:(1)单任务,静止站立;(2)双任务,静止站立并执行一项需要记忆和注意力的任务;(3)静止站立听音乐。

结果

MPH导致在双任务条件下以及听音乐时姿势稳定性有显著改善,而安慰剂对照组未出现同等程度的改善。

结论

MPH可改善ADHD儿童的姿势稳定性,尤其是在执行额外任务时。这可能是由于注意力能力增强,从而有助于在执行需要注意力的任务时改善平衡控制。MPH作为一种潜在的药物治疗方法,有待进一步研究以改善其他临床人群的平衡控制和身体功能。

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