Department of Psychiatry, Sørlandet Hospital HF, Kristiansand, Norway.
Department of Biostatistics, Oslo University Hospital, Norway.
J Atten Disord. 2024 Oct;28(12):1577-1588. doi: 10.1177/10870547241273102. Epub 2024 Sep 2.
Diagnostic assessment of ADHD is challenging due to comorbid psychopathologies and symptoms overlapping with other psychiatric disorders. In this study, we investigate if a distinct pattern of neuromuscular dysregulation previously reported in ADHD, can help identifying ADHD in psychiatric patients with diverse and complex symptoms.
We explored the impact of neuromuscular dysregulation, as measured by The Motor Function Neurologic Assessment (MFNU), on the likelihood of being diagnosed with ADHD, affective disorder, anxiety disorder, or personality disorder among adults ( = 115) referred to a psychiatric outpatient clinic.
Logistic regression revealed that neuromuscular dysregulation was significantly associated with ADHD diagnosis only ( 1.15, < .01), and not with affective-, anxiety-, or personality disorders. Sensitivity and specificity for ADHD at different MFNU scores is provided.
A test of neuromuscular dysregulation may promote diagnostic accuracy in differentiating ADHD from other psychiatric disorders in patients with an overlapping symptom picture. This may have important implications for clinical practice. More studies are needed.
由于共患精神病理学和与其他精神障碍重叠的症状，ADHD 的诊断评估具有挑战性。在这项研究中，我们研究了以前在 ADHD 中报道的神经肌肉调节紊乱的独特模式是否有助于识别具有不同和复杂症状的精神科患者中的 ADHD。
我们探讨了神经肌肉调节紊乱（通过运动功能神经学评估 (MFNU) 测量）对在精神科门诊就诊的成年人（n=115）被诊断为 ADHD、情感障碍、焦虑障碍或人格障碍的可能性的影响。
逻辑回归显示，神经肌肉调节紊乱仅与 ADHD 诊断显著相关（1.15，p<0.01），而与情感障碍、焦虑障碍或人格障碍无关。提供了不同 MFNU 分数下 ADHD 的灵敏度和特异性。
神经肌肉调节紊乱测试可能有助于提高在具有重叠症状的患者中区分 ADHD 与其他精神障碍的诊断准确性。这对临床实践可能具有重要意义。需要更多的研究。
