Neurodegenerative Disorders Research, Perth, Western Australia, Australia.
Intern Med J. 2010 Mar;40(3):209-13. doi: 10.1111/j.1445-5994.2008.01845.x. Epub 2008 Nov 11.
There is limited information on the causes of neurological disorders in an Australian rural setting.
This study reports on a prospective cohort of 160 patients (95 women and 65 men) with a mean age of 55.1 years (standard deviation 19.78 years, range 12-92 years) receiving a neurological work-up from one neurologist attending the Geraldton and Midwest region of Western Australia over a 12-month period.
Patients were divided into 15 diagnostic classifications. Movement disorders were the most common diagnostic classification (38 of 160 or 23.75%) and Parkinson's disease was the most common movement disorder (30 of 38 or 78.95%) with an estimated period of prevalence of 187.5 persons per 1000. Of the other neurological disorder diagnosis classifications the following number of patients per group was observed: epilepsy (27 or 16.87%); neuromuscular disorders (22 or 13.75%); multiple sclerosis (12 or 7.5%); cerebrovascular disease (10 or 6.25%); headaches (7 or 4.37%); neurodegenerative (7 or 4.37%); dementias (6 or 3.75%); memory dysfunction (6 or 3.75%); gait disorders (4 or 2.5%); vestibular syndrome (3 or 1.87%); pain syndrome (3 or 1.87%); sensory syndrome (2 or 1.25%); brain injury (1 or 0.62%) and miscellaneous (12 or 7.5%). A high number of persons having Parkinson's disease was found.
Possible risk factors for Parkinson's disease for individuals living in Geraldton and Midwest region need to be investigated. This study raises issues pertaining to the provision of services and allocation of resources in rural areas, especially for patients with Parkinson's disease.
在澳大利亚农村地区,有关神经障碍病因的信息有限。
本研究报告了一项前瞻性队列研究,纳入了 160 例患者(95 例女性和 65 例男性),平均年龄为 55.1 岁(标准差 19.78 岁,范围 12-92 岁),由一位在澳大利亚西部杰拉尔顿和中西部地区工作的神经科医生进行神经学检查,研究时间为 12 个月。
患者被分为 15 种诊断分类。运动障碍是最常见的诊断分类(160 例中的 38 例或 23.75%),帕金森病是最常见的运动障碍(38 例中的 30 例或 78.95%),估计患病率为每 1000 人中有 187.5 人。其他神经障碍诊断分类中,每组的患者人数如下:癫痫(27 例或 16.87%);神经肌肉疾病(22 例或 13.75%);多发性硬化症(12 例或 7.5%);脑血管疾病(10 例或 6.25%);头痛(7 例或 4.37%);神经退行性疾病(7 例或 4.37%);痴呆(6 例或 3.75%);记忆功能障碍(6 例或 3.75%);步态障碍(4 例或 2.5%);前庭综合征(3 例或 1.87%);疼痛综合征(3 例或 1.87%);感觉综合征(2 例或 1.25%);脑损伤(1 例或 0.62%)和其他(12 例或 7.5%)。发现患有帕金森病的人数较多。
需要调查生活在杰拉尔顿和中西部地区的个体患帕金森病的可能危险因素。本研究提出了有关农村地区服务提供和资源分配的问题,特别是对于帕金森病患者。