Olsen B, Lan P T, Stålsby Lundborg C, Khang T H, Unemo M
School of Health and Medical Sciences, Orebro University, Orebro, Sweden.
J Eur Acad Dermatol Venereol. 2009 May;23(5):533-7. doi: 10.1111/j.1468-3083.2009.03117.x. Epub 2009 Feb 13.
To analyse the prevalence of Mycoplasma genitalium infection in a population-based study among married women from a demographic surveillance site in a rural geographical area of Vietnam.
Women, aged 18-49 years, were randomly selected to participate. DNA was isolated from endocervical swabs sampled from 990 participating women. The M. genitalium MgPa adhesion gene was detected using a real-time polymerase chain reaction with TaqMan probe.
Eight (0.8%; 95% confidence interval, 0.25-1.35%) of the included women were infected with M. genitalium. Two of these positive women reported clinical symptoms. One additional M. genitalium-positive but symptom-free woman, however, showed clinical signs of vaginitis. None of the M. genitalium-positive women was concomitantly infected with Chlamydia trachomatis, Neisseria gonorrhoeae, syphilis or human immunodeficiency virus (HIV). Furthermore, there was no obvious association between M. genitalium infection and vaginal douching, use of intrauterine device, or occurrence of bacterial vaginosis, candidiasis, or Trichomonas vaginalis.
The prevalence of M. genitalium among married women in Vietnam was relatively low. However, more large, well-designed and appropriately performed studies in other population groups including unmarried women and men, and in other geographical areas, rural as well as urban, are crucial in order to extract any evidence-based conclusions regarding the overall prevalence of sexually transmitted infections (STIs), including M. genitalium infections, in the Vietnamese society. The present study compiled with such future studies may form the basis for a national sexual health strategy for prevention, diagnosis, and surveillance of STIs, including M. genitalium infections, in Vietnam.
在越南农村地理区域的一个人口监测点进行的一项基于人群的研究中，分析已婚女性生殖支原体感染的患病率。
随机选取年龄在18至49岁之间的女性参与研究。从990名参与研究的女性宫颈拭子中提取DNA。使用带有TaqMan探针的实时聚合酶链反应检测生殖支原体MgPa粘附基因。
纳入研究的女性中有8人（0.8%；95%置信区间，0.25 - 1.35%）感染了生殖支原体。这些阳性女性中有两人报告有临床症状。然而，另有一名生殖支原体阳性但无症状的女性表现出阴道炎的临床体征。所有生殖支原体阳性女性均未同时感染沙眼衣原体、淋病奈瑟菌、梅毒或人类免疫缺陷病毒（HIV）。此外，生殖支原体感染与阴道灌洗、宫内节育器的使用，或细菌性阴道病、念珠菌病或滴虫性阴道炎的发生之间没有明显关联。
越南已婚女性中生殖支原体的患病率相对较低。然而，在包括未婚女性和男性在内的其他人群组以及其他地理区域（农村和城市）开展更多大规模、设计良好且执行恰当的研究，对于得出关于越南社会包括生殖支原体感染在内的性传播感染（STIs）总体患病率的任何循证结论至关重要。本研究以及此类未来研究可能为越南制定包括生殖支原体感染在内的性传播感染的预防、诊断和监测的国家性健康战略奠定基础。
