硫酸化甾体：来自所罗门群岛海洋海绵Ptilocaulis spiculifer的ptilosteroids A - C以及ptilosaponosides A和B 。
Sulfated steroids: ptilosteroids A-C and ptilosaponosides A and B from the Solomon Islands marine sponge Ptilocaulis spiculifer.
作者信息
Gabant Marion, Schmitz-Afonso Isabelle, Gallard Jean-François, Menou Jean-Louis, Laurent Dominique, Debitus Cécile, Al-Mourabit Ali
机构信息
Institut de Chimie des Substances Naturelles du CNRS, Gif-sur-Yvette, France.
出版信息
J Nat Prod. 2009 Apr;72(4):760-3. doi: 10.1021/np800758c.
Three new pregnanes, ptilosteroid A (1), ptilosteroid B (2), and ptilosteroid C (3), and two new pregnane glycosides, ptilosaponoside A (4) and ptilosaponoside B (5), were isolated from the marine sponge Ptilocaulis spiculifer collected in the Solomon Islands. The structures were determined by spectroscopic methods. Biological tests of these compounds showed that they are not cytotoxic against KB cells.
从在所罗门群岛采集的海洋海绵针状海绵（Ptilocaulis spiculifer）中分离出了三种新的孕甾烷类化合物，即针状甾体A（1）、针状甾体B（2）和针状甾体C（3），以及两种新的孕甾烷糖苷，即针状皂苷A（4）和针状皂苷B（5）。通过光谱方法确定了其结构。对这些化合物的生物学测试表明，它们对KB细胞没有细胞毒性。
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