Jongwutiwes Ubonvan, Malathum Kumthorn, Sungkanuparph Somnuek
Department of Medicine, Faculty of Medicine, Siriraj Hospital, Mahidol University, Bangkok, Thailand.
J Med Assoc Thai. 2007 Nov;90 Suppl 2:85-8.
Atypical presentations of cryptococcal infection have been described as clinical manifestations of immune reconstitution inflammatory syndrome (IRIS) in HIV-infected patients following commence of antiretroviral therapy (ART). The authors describe a patient presenting with cryptococcal meningoradiculitis two weeks after initiation of ART. In patients with advanced HIV disease, immune reconstitution induced by ART can precipitate onset of atypical clinical manifestations in those patients with latent cryptococcal infection of the central nervous system.
隐球菌感染的非典型表现被描述为HIV感染患者在开始抗逆转录病毒治疗（ART）后免疫重建炎症综合征（IRIS）的临床表现。作者描述了一名患者在开始ART两周后出现隐球菌性脑脊神经根炎。在晚期HIV疾病患者中，ART诱导的免疫重建可促使那些中枢神经系统存在潜伏性隐球菌感染的患者出现非典型临床表现。
