心肺运动试验在疑似微血管缺血评估中的应用。
The utility of cardiopulmonary exercise testing in the assessment of suspected microvascular ischemia.
出版信息
Int J Cardiol. 2011 Apr 1;148(1):e7-9. doi: 10.1016/j.ijcard.2009.01.055. Epub 2009 Feb 23.
Abstract
Evidence demonstrating the potential value of cardiopulmonary exercise testing (CPET) to accurately detect myocardial ischemia secondary to macro-vascular disease is beginning to emerge. Despite distinct mechanisms mediating ischemia in micro-vascular and macrovascular coronary artery disease (CAD), the net physiologic effect of exercise-induced left ventricular (LV) dysfunction is common to both. The abnormal physiologic response to CPET may, therefore, be similar in patients with macro- and micro-vascular ischemia. The following case report describes the CPET abnormalities in a patient with suspected microvascular CAD and the subsequent improvement in LV function following three weeks of medical therapy with the anti-ischemic drug ranolazine.
摘要
有证据表明，心肺运动测试（CPET）具有潜在的价值，可以准确检测到由大血管疾病引起的心肌缺血。尽管微血管和大血管冠状动脉疾病（CAD）的缺血机制不同，但运动引起的左心室（LV）功能障碍的净生理效应对两者都是共同的。因此，患有大血管和微血管缺血的患者的 CPET 异常可能相似。以下病例报告描述了一名疑似微血管 CAD 患者的 CPET 异常情况，以及随后在接受抗缺血药物雷诺嗪治疗 3 周后 LV 功能的改善。
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