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每日或每周使用氯己定漱口对老年人群口腔健康的治疗效果。

Therapeutic effects of daily or weekly chlorhexidine rinsing on oral health of a geriatric population.

作者信息

Persson R E, Truelove E L, LeResche L, Robinovitch M R

机构信息

Department of Oral Medicine, Health Sciences Center, University of Washington, Seattle.

出版信息

Oral Surg Oral Med Oral Pathol. 1991 Aug;72(2):184-91. doi: 10.1016/0030-4220(91)90161-5.

Abstract

The effects of a chlorhexidine rinse on salivary Streptococcus mutans, Lactobacillus, and Candida albicans counts and on periodontal conditions (gingival index, plaque index, pocket depths) were studied in 42 elderly subjects. Under supervision, they rinsed either daily or weekly for 6 weeks with a 0.12% chlorhexidine solution (Peridex). Saliva samples were taken for chemical and microbiologic examinations, and periodontal conditions were assessed at baseline, week 6, and 6 weeks after final rinse. Significantly lower S. mutans counts were found at week 6 for both rinsing groups (p less than 0.001). Lactobacillus and Candida counts were also generally lower at week 6, with the clearest improvement among persons with the highest counts of bacteria and yeast. Periodontal conditions were improved at week 6 (p less than 0.001) in both groups. Such improvements were not maintained 6 weeks after the rinsing regimen was completed. At baseline poor oral conditions were noticed, which placed most of the subjects at risk for tooth decay and periodontal disease. Without any other dental procedures but daily or weekly supervised rinsing, oral conditions were improved and this risk was reduced. Daily rinsing was not superior to weekly rinsing with 0.12% chlorhexidine.

摘要

在42名老年受试者中研究了洗必泰漱口水对唾液中变形链球菌、乳酸杆菌和白色念珠菌数量以及牙周状况(牙龈指数、菌斑指数、牙周袋深度)的影响。在监督下,他们每天或每周用0.12%的洗必泰溶液(派丽奥)漱口6周。采集唾液样本进行化学和微生物学检查,并在基线、第6周和最后一次漱口后6周评估牙周状况。两个漱口组在第6周时变形链球菌数量均显著降低(p<0.001)。第6周时乳酸杆菌和念珠菌数量通常也较低,在细菌和酵母菌数量最高的人群中改善最为明显。两组在第6周时牙周状况均有所改善(p<0.001)。在漱口方案完成6周后,这些改善并未维持。在基线时发现口腔状况较差,这使大多数受试者有患龋齿和牙周病的风险。在没有任何其他牙科治疗的情况下,仅通过每天或每周监督漱口,口腔状况得到改善,风险降低。每天漱口并不优于每周用0.12%洗必泰漱口。

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