Quantitative analysis of the cross-correlation between pattern ERG and pattern VEP.

The cross-correlation between PVEPs and PERG was investigated. (1) There were high correlations between PVEPs recorded from the inion and those from points Oz, Pz, Cz, and Fz in the range of 75-150 msec following pattern visual stimulation to the eyes although no correlation was found in the range 0-75 msec. (2) PVEPs recorded from the inion highly correlated with PERG in the 75-150 msec range but not in the 0-75 msec range. It suggests that the late negative component included in the PERG reflected the electrotonically spread at the eye level of PVEP. (3) Intra-individual reproducibility was studied. PVEPs showed a high reproducibility in the 75-150 msec range, but not in the 0-75 msec range. The reproducibility of PERG was high in the 0-75 msec range but also in the 75-150 msec range, where PERG reflected PVEPs. These results suggest that the early positive component of PERG was specific to the cell activities in the retina to the pattern visual stimulus, and had an origin different from the brain activity for PVEPs.