Perloff J J, McDermott M T, Perloff K G, Blue P W, Enzenhauer R, Sieck E, Chantelois A E, Dolbow A, Kidd G S
Nuclear Medicine Service, Fitzsimons Army Medical Center, Aurora, Colorado.
Orthop Rev. 1991 Aug;20(8):690-8.
To evaluate skeletal osteopenia as a risk factor for hip fractures, we measured bone-mineral content in 18 postmenopausal women (aged 50 to 85 years) within 5 days of sustaining a nontraumatic hip fracture. We compared these findings to those in 50 women without a hip fracture who were matched for age, postmenopausal years, height, and weight to the study participants. With the use of dual-photon absorptiometry, the hip fracture patients were found to have a significantly reduced mean bone-mineral content (P less than .005) at three sites in the unaffected hip and a marginally lower mean value (P less than .057) in the lumbar spine as compared to the controls. Other findings in the fracture group included a history of little physical activity, diminished visual acuity, and a somewhat high prevalence of psychiatric/organic brain disorders. Reduced bone mass is an important risk factor for hip fractures. However, other conditions such as physical inactivity, reduced visual acuity, and cognitive impairment may also affect the tendency to fall and/or the ability to cushion the impact of a fall and thus further increase the risk of fracture occurrence.
为评估骨骼骨质减少作为髋部骨折的一个风险因素，我们在18名绝经后女性（年龄50至85岁）发生非创伤性髋部骨折后5天内测量了她们的骨矿物质含量。我们将这些结果与50名未发生髋部骨折的女性进行比较，这些女性在年龄、绝经年限、身高和体重方面与研究参与者相匹配。使用双能光子吸收法发现，与对照组相比，髋部骨折患者在未受影响的髋部三个部位的平均骨矿物质含量显著降低（P小于0.005），在腰椎的平均值略低（P小于0.057）。骨折组的其他发现包括身体活动少的病史、视力下降以及精神/器质性脑疾病的患病率略高。骨量减少是髋部骨折的一个重要风险因素。然而，其他情况，如身体不活动、视力下降和认知障碍，也可能影响跌倒倾向和/或缓冲跌倒冲击力的能力，从而进一步增加骨折发生的风险。
