果蝇诺拉病毒是一种肠道病毒，通过粪便传播。

The Drosophila Nora virus is an enteric virus, transmitted via feces.

作者信息

Habayeb Mazen S, Cantera Rafael, Casanova Gabriela, Ekström Jens-Ola, Albright Shannon, Hultmark Dan

机构信息

Department of Molecular Biology, By. 6L, Umeå University, S-90187 Umeå, Sweden.

出版信息

J Invertebr Pathol. 2009 Apr;101(1):29-33. doi: 10.1016/j.jip.2009.02.003. Epub 2009 Feb 21.

DOI:10.1016/j.jip.2009.02.003

PMID:19236875

Abstract

The biology of the Drosophila viruses has not been intensely investigated. Here we have investigated the biology of the Nora virus, a persistent Drosophila virus. We find that injected Nora virus is able to replicate in the files, reaching a high titer that is maintained in the next generation. There is a remarkable variation in the viral loads of individual flies in persistently infected stocks; the titers can differ by three orders of magnitude. The Nora virus is mainly found in the intestine of infected flies, and the histology of these infected intestines show increased vacuolization. The virus is excreted in the feces and is horizontally transmitted. The Nora virus infection has a very mild effect on the longevity of the flies, and no significant effect on the number of eggs laid and the percent of eggs that develop to adults.

摘要

果蝇病毒的生物学特性尚未得到深入研究。在此，我们对一种持久性果蝇病毒——诺拉病毒的生物学特性进行了研究。我们发现，注射的诺拉病毒能够在果蝇体内复制，达到高滴度，并在下一代中保持。在持续感染的果蝇种群中，个体果蝇的病毒载量存在显著差异；滴度可相差三个数量级。诺拉病毒主要存在于受感染果蝇的肠道中，这些受感染肠道的组织学显示空泡化增加。该病毒通过粪便排出并进行水平传播。诺拉病毒感染对果蝇的寿命影响非常轻微，对产卵数量和发育成成虫的卵的百分比没有显著影响。