[基于杂质谱鉴定甲基苯丙胺关联样本的研究]

[Study on the linked samples of methamphetamine identified by the impurity profile].

作者信息

Zhang Jianxin, Zhang Daming, Qiao Jing, Yang Shiyun

机构信息

Forensic Medical examination Center of Beijing Public Security Bureau, Beijing 100085, China.

出版信息

Wei Sheng Yan Jiu. 2008 Nov;37(6):736-9, 744.

PMID:19239014

Abstract

OBJECTIVE

To compare and classify the samples of MA crystals by using impurity profile to offer methods for identification of linked samples.

METHODS

50 mg samples of MA were dissolved in 1 ml of buffer solution (pH 7.0, four parts of 0.1 mol/L phosphate buffer, and one part of 10% Na2CO3), impurities were extracted with 0.5 ml of ethyl acetate containing four internal standards (n-decane, n-pentadecane, n-eicosane and n-octacosane) and analyzed by gas chromatography with a flame ionization detector on a DB-5 capillary column (30 m x 0.32 mm i.d. x 1.0 microm). Seventeen characteristic peaks on chromatograms were selected for the comparison and classification of samples, and the data were evaluated by the Euclidean distance of the relative peak areas after logarithmic transformation.

RESULTS

Eight different batches of MA (six samples from each batch) to be seized by the Beijing Public Security Bureau (BPSB) in 2006-2007 were analyzed. The results indicated that the samples from the same batch were successfully classified into one group.

CONCLUSION

The methods could be very useful for identifying the linked samples and could provide technique foundation for MA drug criminal inspection.

摘要

目的

通过杂质剖析对甲基苯丙胺（MA）晶体样本进行比较和分类，为关联样本的鉴定提供方法。

方法

将50mg的MA样本溶解于1ml缓冲溶液（pH 7.0，由四份0.1mol/L磷酸盐缓冲液和一份10%碳酸钠组成）中，用0.5ml含有四种内标物（正癸烷、正十五烷、正二十烷和正二十八烷）的乙酸乙酯萃取杂质，并在DB - 5毛细管柱（30m×0.32mm内径×1.0μm）上用火焰离子化检测器通过气相色谱法进行分析。选择色谱图上的17个特征峰用于样本的比较和分类，并通过对数转换后相对峰面积的欧几里得距离对数据进行评估。