[从经干扰素处理的细胞中分离的RNA制剂的抗病毒活性（抗病毒蛋白的信使RNA？）]
[Antiviral activity of preparations of RNA isolated from cells treated with interferon (messenger RNA for an antiviral protein?)].
作者信息
Orlova T G, Mamontova T V, Zhdanova L V, Solov'ev V D
出版信息
Biull Eksp Biol Med. 1977 Apr;83(4):436-7.
PMID:192394
Abstract
Chick embryo cultures treated with interferon yielded a biologically active RNA which, upon inoculation into chick embryo cells, created an antiviral condition in them. The level of vesicular stomatitis virus reproduction in such cells was 2-30% of that observed in the cells treated with control RNA. The maximum activity of the experimental RNA was seen 3 hours after the treatment with interferon.
摘要
用干扰素处理的鸡胚培养物产生了一种生物活性RNA，将其接种到鸡胚细胞中后，会在细胞中产生抗病毒状态。在这些细胞中，水疱性口炎病毒的繁殖水平是用对照RNA处理的细胞中观察到的繁殖水平的2%至30%。在用干扰素处理3小时后，实验性RNA的活性达到最高。
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