Jang Se Youn, Kong Min Ho, Hymanson Henry J, Jin Tae Kyung, Song Kwan Young, Wang Jeffrey C
Department of Neurosurgery, Seoul Medical Center, Seoul, Korea.
J Korean Neurosurg Soc. 2009 Jan;45(1):24-31. doi: 10.3340/jkns.2009.45.1.24. Epub 2009 Jan 31.
To investigate the effectiveness of radiographic parameters on segmental instability in the lumbar spine using Kinetic magnetic resonance imaging (MRI).
Segmental motion, defined as excessive (more than 3 mm) translational motion from flexion to extension, was investigated in 309 subjects (927 segments) using Kinetic MRI. Radiographic parameters which can help indicate segmental instability include disc degeneration (DD), facet joint osteoarthritis (FJO), and ligament flavum hypertrophy (LFH). These three radiographic parameters were simultaneously evaluated, and the combinations corresponding to significant segmental instability at each level were determined.
The overall incidence of segmental instability was 10.5% at L3-L4, 16.5% at L4-L5, and 7.3% at L5-S1. DD and LFH at L3-L4 and FJO and LFH at L4-L5 were individually associated with segmental instability (p<0.05). At L4-L5, the following combinations had a higher incidence of segmental instability (p<0.05) when compared to other segments : (1) Grade IV DD with grade 3 FJO, (2) Grade 2 or 3 FJO with the presence of LFH, and (3) Grade IV DD with the presence of LFH. At L5-S1, the group with Grade III disc and Grade 3 FJO had a higher incidence of segmental instability than the group with Grade I or II DD and Grade 1 FJO.
This study showed that the presences of either Grade IV DD or grade 3 FJO with LFH at L4-L5 were good indicators for segmental instability. Therefore, using these parameters simultaneously in patients with segmental instability would be useful for determining candidacy for surgical treatment.
使用动态磁共振成像(MRI)研究影像学参数对腰椎节段性不稳定的有效性。
采用动态MRI对309名受试者(927个节段)进行节段性运动研究,节段性运动定义为从屈曲到伸展时过度(超过3毫米)的平移运动。有助于指示节段性不稳定的影像学参数包括椎间盘退变(DD)、小关节骨关节炎(FJO)和黄韧带肥厚(LFH)。同时评估这三个影像学参数,并确定每个节段对应显著节段性不稳定的组合。
L3-L4节段性不稳定的总体发生率为10.5%,L4-L5为16.5%,L5-S1为7.3%。L3-L4节段的DD和LFH以及L4-L5节段的FJO和LFH分别与节段性不稳定相关(p<0.05)。在L4-L5节段,与其他节段相比,以下组合的节段性不稳定发生率更高(p<0.05):(1)IV级DD伴3级FJO;(2)2级或3级FJO伴LFH;(3)IV级DD伴LFH。在L5-S1节段,III级椎间盘伴3级FJO组的节段性不稳定发生率高于I级或II级DD伴1级FJO组。
本研究表明,L4-L5节段IV级DD或3级FJO伴LFH是节段性不稳定的良好指标。因此,在节段性不稳定患者中同时使用这些参数将有助于确定手术治疗的候选资格。