Tawil Peter Zahi, Trope Martin, Curran Alice E, Caplan Daniel J, Kirakozova Anna, Duggan Derek J, Teixeira Fabricio B
Department of Endodontics, University of North Carolina-Chapel Hill, School of Dentistry, Chapel Hill, NC, USA.
J Endod. 2009 Mar;35(3):357-62. doi: 10.1016/j.joen.2008.12.001.
The purpose of this study was to assess the healing of periapical tissues using three different materials (IRM [L.D. Caulk Inc, Dentsply International Inc, Milford, DE], Geristore [Den-Mat, Santa Maria, CA], and MTA [ProRoot MTA; Dentsply Tulsa Dental Specialties, Tulsa, OK]) after endodontic microsurgery in an animal model. Using beagle dogs as a study model, 48 bicuspids were accessed, instrumented, and intentionally infected. The surgical procedures were performed after 30 days following the radiographic confirmation of periapical radiolucencies. The root canals were still infected and had no disinfection procedure carried out. The root ends were resected, retrograde preparations were completed, and the experimental materials were placed under surgical operating microscopy. After a period of 6 months, digital radiographic images of the periradicular areas were taken. The samples were prepared for histologic evaluation. Although Geristore showed no radiographic difference when compared with the other groups, it showed the least favorable healing in the histologic evaluation. Our histologic and radiographic results showed no statistical difference between MTA and IRM.
本研究的目的是在动物模型中评估牙髓显微外科手术后使用三种不同材料（IRM [L.D. Caulk公司，登士柏国际公司，米尔福德，特拉华州]、Geristore [丹特马特公司，圣玛丽亚，加利福尼亚州] 和MTA [ProRoot MTA；登士柏塔尔萨牙科专业公司，塔尔萨，俄克拉何马州]）时根尖周组织的愈合情况。以比格犬作为研究模型，对48颗双尖牙进行开髓、预备，并故意感染。在根尖周透射影经影像学确认30天后进行手术操作。根管仍有感染，未进行消毒处理。切除根尖，完成倒预备，并在手术显微镜下放置实验材料。6个月后，拍摄根尖周区域的数字化影像。制备样本进行组织学评估。尽管与其他组相比，Geristore在影像学上没有差异，但在组织学评估中其愈合情况最不理想。我们的组织学和影像学结果显示，MTA和IRM之间没有统计学差异。
