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评估和定义人工晶状体的锐利度:市售方形边缘亲水性人工晶状体的微边缘结构

Evaluating and defining the sharpness of intraocular lenses: microedge structure of commercially available square-edged hydrophilic intraocular lenses.

作者信息

Werner Liliana, Tetz Manfred, Feldmann Ines, Bücker Michael

机构信息

Berlin Eye Research Institute, Berlin, Germany.

出版信息

J Cataract Refract Surg. 2009 Mar;35(3):556-66. doi: 10.1016/j.jcrs.2008.11.042.

DOI:10.1016/j.jcrs.2008.11.042
PMID:19251151
Abstract

PURPOSE

To evaluate the microstructure of the edges of currently available hydrophilic acrylic intraocular lenses (IOLs) in terms of their deviation from an "ideal" square as a follow-up of preliminary in vitro studies of experimental poly(methyl methacrylate) IOLs and commercially available foldable hydrophobic IOLs.

SETTING

Berlin Eye Research Institute, Berlin, Germany.

METHODS

Twenty-four designs of hydrophilic acrylic IOLs were used in this study. For each design, a +20.0 diopter (D) IOL and a +0.0 D IOL (or the lowest available plus dioptric power) were evaluated. The IOL edge was imaged under low-vacuum (0.7 torr), high-magnification scanning electron microscopy (SEM) using an environmental microscope and standardized technique. The photographs were imported to a digital computer program, and the area above the posterior-lateral edge, representing the deviation from a perfect square, was measured in square microns.

RESULTS

Currently available hydrophilic acrylic IOLs labeled as square edged had an area of deviation from a perfect square ranging from 60.84 to 871.51 microm(2) for the +20.0 D IOLs and from 35.52 to 826.55 microm(2) for the low-diopter IOLs. Although some differences in edge finishing between the IOLs analyzed were observed, edge surfaces of hydrophilic acrylic IOLs appeared overall smooth under environmental SEM.

CONCLUSIONS

Analysis of the microstructure of the optic edge of currently available square-edged hydrophilic acrylic IOLs showed a large variation of the deviation area from a perfect square.

摘要

目的

作为对实验性聚甲基丙烯酸甲酯人工晶状体和市售可折叠疏水人工晶状体初步体外研究的后续,根据目前市售亲水性丙烯酸人工晶状体(IOL)边缘与“理想”正方形的偏差来评估其微观结构。

设置

德国柏林眼研究所。

方法

本研究使用了24种亲水性丙烯酸IOL设计。对于每种设计,评估了一个+20.0屈光度(D)的IOL和一个+0.0 D的IOL(或最低可用的正屈光度)。使用环境显微镜和标准化技术,在低真空(0.7托)、高放大倍数扫描电子显微镜(SEM)下对IOL边缘进行成像。将照片导入数字计算机程序,并测量后外侧边缘上方代表与完美正方形偏差的面积,单位为平方微米。

结果

对于+20.0 D的IOL,目前标记为方形边缘的亲水性丙烯酸IOL与完美正方形的偏差面积范围为60.84至871.51平方微米,对于低屈光度IOL,偏差面积范围为35.52至826.55平方微米。尽管在所分析的IOL之间观察到边缘处理存在一些差异,但在环境SEM下,亲水性丙烯酸IOL的边缘表面总体上看起来很光滑。

结论

对目前市售方形边缘亲水性丙烯酸IOL光学边缘微观结构的分析表明,与完美正方形的偏差面积存在很大差异。

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