Sussex Eye Hospital, Brighton and Sussex University Hospitals NHS Trust, Brighton, England; Brighton and Sussex Medical School, University of Sussex, Falmer, England.
Sussex Eye Hospital, Brighton and Sussex University Hospitals NHS Trust, Brighton, England; Medical Faculty, Otto von Guericke University, Magdeburg, Germany.
J Cataract Refract Surg. 2019 Jun;45(6):847-853. doi: 10.1016/j.jcrs.2018.12.004. Epub 2019 Mar 28.
To analyze the sharpness of the posterior optic edge and edge thickness of intraocular lenses (IOLs) marketed with a square-edged profile.
University of Brighton and Brighton and Sussex University Hospitals NHS Trust, Brighton, England.
Laboratory study.
Fourteen square-edged 20.0 diopter IOLs were analyzed, including 9 hydrophobic IOLs (AF-1, AF-1 iSert, Clareon, EyeCee One Crystal, CT Lucia, Envista, EyeCee One, Vivinex iSert, and RayOne Hydrophobic) and 5 hydrophilic IOLs (Asphira, CT Asphina, Incise, Synthesis, and RayOne Hydrophilic). All the IOLs were scanned following a previously published standardized technique using environmental scanning electron microscopy. The posterior optic edges were scanned at a magnification of ×500 and ×200 to measure the radius of curvature of the posterior optic edges and the optic edge thickness.
The radius of curvature of the posterior optic edges ranged from 4.6 to 20.6 μm. Except for the Incise IOL (7.7 μm), all hydrophilic IOLs (Synthesis [10.6 μm], Asphira [13.7 μm], RayOne Hydrophilic [14.0 μm], CT Asphina [13.7 μm]) had a radius of curvature greater than 10.0 μm. For the hydrophobic IOLs, the radius of curvature was less than 10.0 μm for the Clareon (7.9 μm), EyeCee One Crystal (4.7 μm), Vivinex iSert (7.6 μm), and CT Lucia (4.6 μm), and greater than 10.0 μm for the Envista (19.7 μm), EyeCee One (13.7 μm), AF-1 iSert (19.7 μm), AF-1 (19.7 μm) and the RayOne Hydrophobic (20.6 μm). The Vivinex iSert (150.5 μm) and the Incise (218.2 μm) were the thinnest IOLs, and the RayOne Hydrophobic (375.8 μm) and RayOne Hydrophilic IOLs (477.1 μm) were the thickest of the hydrophobic and hydrophilic IOLs, respectively.
Commercially marketed square-edged IOLs still differed in the sharpness of the posterior optic edge. More hydrophobic IOLs have rounder edges than those studied 10 years ago. Variations in the edge profile of hydrophobic IOLs were greater compared with the hydrophilic IOLs.
分析具有方形边缘轮廓的市售人工晶状体（IOL）的后光学边缘的锐利度和边缘厚度。
英国布莱顿大学和布莱顿和苏塞克斯大学医院国民保健制度信托基金会。
实验室研究。
分析了 14 个方形边缘 20.0 屈光度 IOL，包括 9 个疏水性 IOL（AF-1、AF-1 iSert、Clareon、EyeCee One Crystal、CT Lucia、Envista、EyeCee One、Vivinex iSert 和 RayOne Hydrophobic）和 5 个亲水性 IOL（Asphira、CT Asphina、Incise、Synthesis 和 RayOne Hydrophilic）。所有 IOL 均按照先前发表的标准化技术使用环境扫描电子显微镜进行扫描。以 500 倍和 200 倍放大倍率扫描后光学边缘，以测量后光学边缘的曲率半径和光学边缘厚度。
后光学边缘的曲率半径范围为 4.6 至 20.6μm。除 Incise IOL（7.7μm）外，所有亲水性 IOL（Synthesis[10.6μm]、Asphira[13.7μm]、RayOne Hydrophilic[14.0μm]、CT Asphina[13.7μm]）的曲率半径均大于 10.0μm。对于疏水性 IOL，Clareon（7.9μm）、EyeCee One Crystal（4.7μm）、Vivinex iSert（7.6μm）和 CT Lucia（4.6μm）的曲率半径小于 10.0μm，而 Envista（19.7μm）、EyeCee One（13.7μm）、AF-1 iSert（19.7μm）、AF-1（19.7μm）和 RayOne Hydrophobic（20.6μm）的曲率半径大于 10.0μm。Vivinex iSert（150.5μm）和 Incise（218.2μm）是最薄的 IOL，而 RayOne Hydrophobic（375.8μm）和 RayOne Hydrophilic IOL（477.1μm）分别是疏水性和亲水性 IOL 中最厚的。
市售的具有方形边缘的 IOL 在后光学边缘的锐利度上仍然存在差异。与 10 年前相比，更多的疏水性 IOL 具有更圆的边缘。与亲水性 IOL 相比，疏水性 IOL 的边缘轮廓变化更大。
