Flory Janine D, Manuck Stephen B
Department of Psychology, Queens College, 65-30 Kissena Blvd., Flushing, NY 11367, USA.
Psychosom Med. 2009 May;71(4):431-7. doi: 10.1097/PSY.0b013e3181988c2d. Epub 2009 Feb 27.
Varying aspects of impulsive personality have been associated with tobacco use in cross-sectional and prospective studies, including novelty seeking and (low) constraint but most studies have not examined more than one tobacco use phenotype (e.g., any tobacco use versus dependence) or considered more than one variety of impulsiveness simultaneously.
The current study was conducted to evaluate the association of impulsive personality features with multiple tobacco use phenotypes including smoking status, lifetime tobacco consumption, and dependence in a sample of 1284 adults between the ages of 30 and 54. Participants completed multiple self-report measures of impulsive personality and were interviewed regarding lifetime tobacco use.
Results revealed that reward seeking and disinhibitory traits were both associated with smoking status but only disinhibition was associated with tobacco dependence, after controlling for reward seeking.
The results reported here may aid investigations aimed at identifying neurobiological, including genetic, correlates of tobacco use and dependence by providing potential behavioral correlates of the diversity of tobacco use phenotypes. Moreover, successful efforts to prevent tobacco-related disease through prevention or cessation programs will be facilitated by the identification of factors that are differentially associated with different smoking phenotypes.
在横断面研究和前瞻性研究中,冲动型人格的不同方面与烟草使用有关,包括寻求新奇和(低)约束性,但大多数研究未考察超过一种烟草使用表型(如任何烟草使用与烟草依赖),也未同时考虑多种冲动性。
本研究旨在评估冲动型人格特征与多种烟草使用表型之间的关联,这些表型包括吸烟状况、终生烟草消费量以及对1284名年龄在30至54岁之间的成年人样本的烟草依赖情况。参与者完成了多项冲动型人格的自我报告测量,并接受了关于终生烟草使用情况的访谈。
结果显示,在控制寻求奖励因素后,寻求奖励和去抑制性特质均与吸烟状况有关,但只有去抑制性与烟草依赖有关。
此处报告的结果可能有助于开展旨在确定烟草使用和依赖的神经生物学(包括遗传学)相关因素的研究,通过提供烟草使用表型多样性的潜在行为相关因素来实现。此外,通过预防或戒烟项目成功预防烟草相关疾病的努力,将因识别出与不同吸烟表型有差异关联的因素而得到促进。