创伤后应激障碍的暴露时间和剂量反应模型。
Duration of exposure and the dose-response model of PTSD.
机构信息
University of Washington Medical School, Department of Psychiatry and Behavioral Sciences, Box 356560, Seattle,WA 98195-0650, USA.
出版信息
J Interpers Violence. 2010 Jan;25(1):63-74. doi: 10.1177/0886260508329131. Epub 2009 Feb 27.
Abstract
A dose-response model underlies posttraumatic stress disorder (PTSD) and posits a relationship between event magnitude and clinical outcome. The present study examines whether one index of event magnitude--duration of exposure--contributes to risk of PTSD among female victims of sexual assault. Findings support a small but significant contribution of event duration to clinical status in the immediate aftermath of trauma but not at 3-month follow-up. The opposite pattern is obtained for subjective appraisals of threat. These findings add to a growing literature that suggests that a simple application of the dose-response model to objective event characteristics may be insufficient to explain the risk of PTSD.
摘要
创伤后应激障碍（PTSD）存在剂量反应模型，该模型假设事件严重程度与临床结果之间存在关系。本研究检验了事件严重程度的一个指标——暴露持续时间——是否会增加性侵犯女性受害者患 PTSD 的风险。研究结果支持在创伤后即刻，暴露持续时间对临床状况有较小但显著的影响，但在 3 个月随访时没有影响。主观威胁评估则呈现出相反的模式。这些发现增加了越来越多的文献，表明简单地将剂量反应模型应用于客观事件特征可能不足以解释 PTSD 的风险。
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