Boni Luigi, Dionigi Gianlorenzo, Rovera Francesca, Di Giuseppe Matteo
Minimally Invasive Surgery Research Center, Department of Surgical Sciences, University of Insubria.
J Vis Exp. 2009 Feb 27(24):1118. doi: 10.3791/1118.
Caroli's disease is defined as a abnormal dilatation of the intra-hepatica bile ducts: Its incidence is extremely low (1 in 1,000,000 population) and in most of the cases the whole liver is interested and liver transplantation is the treatment of choice. In case of dilatation limited to the left or right lobe, liver resection can be performed. For many year the standard approach for liver resection has been a formal laparotomy by means of a large incision of abdomen that is characterized by significant post-operatie morbidity. More recently, minimally invasive, laparoscopic approach has been proposed as possible surgical technique for liver resection both for benign and malignant diseases. The main benefits of the minimally invasive approach is represented by a significant reduction of the surgical trauma that allows a faster recovery a less post-operative complications. This video shows a case of Caroli s disease occured in a 58 years old male admitted at the gastroenterology department for sudden onset of abdominal pain associated with fever (> 38 C degrees), nausea and shivering. Abdominal ultrasound demonstrated a significant dilatation of intra-hepatic left sited bile ducts with no evidences of gallbladder or common bile duct stones. Such findings were confirmed abdominal high resolution computer tomography. Laparoscopic left sectoriectomy was planned. Five trocars and 30 degrees optic was used, exploration of the abdominal cavity showed no adhesions or evidences of other diseases. In order to control blood inflow to the liver, vascular clamp was placed on the hepatic pedicle (Pringle s manouvre), Parenchymal division is carried out with a combined use of 5 mm bipolar forceps and 5 mm ultrasonic dissector. A severely dilated left hepatic duct was isolated and divided using a 45 mm endoscopic vascular stapler. Liver dissection was continued up to isolation of the main left portal branch that was then divided with a further cartridge of 45 mm vascular stapler. At his point the left liver remains attached only by the left hepatic vein: division of the triangular ligament was performed using monopolar hook and the hepatic vein isolated and the divided using vascular stapler. Haemostatis was refined by application of argon beam coagulation and no bleeding was revealed even after removal of the vascular clamp (total Pringle s time 27 minutes). Postoperative course was uneventful, minimal elevation of the liver function tests was recorded in post-operative day 1 but returned to normal at discharged on post-operative day 3.
其发病率极低(每100万人中1例),在大多数情况下整个肝脏都会受累,肝移植是首选治疗方法。如果扩张仅限于左叶或右叶,则可进行肝切除术。多年来,肝切除的标准方法一直是通过腹部大切口进行正规剖腹手术,其特点是术后发病率较高。最近,微创腹腔镜手术方法已被提议作为肝切除治疗良性和恶性疾病的一种可能的手术技术。微创方法的主要优点是显著减少手术创伤,从而实现更快的恢复和更少的术后并发症。本视频展示了一名58岁男性的卡罗里病病例,该患者因突发腹痛伴发热(>38摄氏度)、恶心和寒战入住胃肠病科。腹部超声显示肝内左侧胆管明显扩张,未发现胆囊或胆总管结石。腹部高分辨率计算机断层扫描证实了这些发现。计划进行腹腔镜左半肝切除术。使用了5个套管针和30度的观察镜,腹腔探查未发现粘连或其他疾病迹象。为了控制肝脏的血流,在肝蒂上放置血管夹(普林格尔手法),使用5毫米双极钳和5毫米超声分离器联合进行实质分离。分离出一条严重扩张的左肝管,并用45毫米内镜血管吻合器进行切断。继续进行肝脏分离,直至分离出左主门静脉分支,然后再用一个45毫米血管吻合器钉仓将其切断。此时,左肝仅通过左肝静脉相连:使用单极钩切断三角韧带,分离并切断肝静脉。通过氩束凝固完善止血,即使移除血管夹后也未发现出血(普林格尔手法总时长27分钟)。术后过程顺利,术后第1天肝功能检查仅有轻微升高,但术后第3天出院时恢复正常。