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抗生素与阑尾切除术治疗急性阑尾炎疗效的Meta分析。

Meta-analysis of the therapeutic effects of antibiotic versus appendicectomy for the treatment of acute appendicitis.

作者信息

Liu Zhi-Hua, Li Chao, Zhang Xing-Wei, Kang Liang, Wang Jian-Ping

机构信息

Department of Colorectal Surgery, The Sixth Affiliated Hospital to Sun Yat-Sen University, Guangzhou, Guangdong 510655, P.R. China.

出版信息

Exp Ther Med. 2014 May;7(5):1181-1186. doi: 10.3892/etm.2014.1584. Epub 2014 Feb 25.

DOI:10.3892/etm.2014.1584
PMID:24940408
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3991548/
Abstract

Appendicectomy has been the gold standard treatment of acute appendicitis for more than a century, while nonoperative therapies, including antibiotics, have acquired increased interest in recent years. The present meta-analysis aimed to compare the therapeutic effects of antibiotics versus appendicectomy for the treatment of acute appendicitis. Medline, Embase and The Cochrane Library databases were searched. Prospective randomized controlled trials that compared antibiotic treatment with surgery were included. The outcomes evaluated included the time of hospital stay, complications and time to work. There were no statistically significant differences between the antibiotic and appendicectomy groups with regard to the time of hospital stay and complications. However, the time to work was significantly longer in the appendicectomy group when compared with the antibiotic group. In addition, the therapeutic effects of antibiotics and appendicectomy were comparable for the treatment of acute appendicitis.

摘要

一个多世纪以来，阑尾切除术一直是急性阑尾炎的金标准治疗方法，而近年来，包括抗生素在内的非手术疗法越来越受到关注。本荟萃分析旨在比较抗生素与阑尾切除术治疗急性阑尾炎的疗效。检索了Medline、Embase和Cochrane图书馆数据库。纳入了比较抗生素治疗与手术治疗的前瞻性随机对照试验。评估的结果包括住院时间、并发症和恢复工作时间。抗生素组和阑尾切除组在住院时间和并发症方面没有统计学上的显著差异。然而，与抗生素组相比，阑尾切除组的恢复工作时间明显更长。此外，抗生素和阑尾切除术治疗急性阑尾炎的疗效相当。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5ba2/3991548/151f1ab5dc71/ETM-07-05-1181-g04.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5ba2/3991548/8bbe30ab5a36/ETM-07-05-1181-g00.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5ba2/3991548/7c35f37ecb89/ETM-07-05-1181-g01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5ba2/3991548/4dea664c02f9/ETM-07-05-1181-g02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5ba2/3991548/392e4e49dd21/ETM-07-05-1181-g03.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5ba2/3991548/151f1ab5dc71/ETM-07-05-1181-g04.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5ba2/3991548/8bbe30ab5a36/ETM-07-05-1181-g00.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5ba2/3991548/7c35f37ecb89/ETM-07-05-1181-g01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5ba2/3991548/4dea664c02f9/ETM-07-05-1181-g02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5ba2/3991548/392e4e49dd21/ETM-07-05-1181-g03.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5ba2/3991548/151f1ab5dc71/ETM-07-05-1181-g04.jpg

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